Impact of a parenting program on maternal sensitivity and infant health
Official title: The Impact of Stress and Caregiver Sensitivity on Infant Cellular Aging in a Population of Under-Resourced Families: A Randomized Controlled Trial
Run by University of Washington · NCT06740266 · Data updated 2026-11-12
This study is testing if a parenting program can help mothers be more sensitive to their babies and improve their health, especially for families who might not have as many resources.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 250 (estimated) |
| Sponsor | University of Washington Academic / other |
| Locations | 1 site (Raleigh, North Carolina) |
| Status | Recruiting |
| Started | December 13, 2024 |
| Main results expected | May 2028 |
| Study ends | April 2029 |
| Registry record updated | February 6, 2026 |
| Trial ID | NCT06740266 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include biological mothers of infants aged 3-12 months who are English- or Spanish-speaking and receiving Medicaid.
✕Probably not a fit
Patients experiencing acute crises, such as hospitalization or homelessness, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to investigate how an evidence-based parenting program, Promoting First Relationships® in Primary Care (PFR in PC), affects maternal sensitivity and infant cellular aging in under-resourced families. Participants will be randomly assigned to receive either the PFR intervention or usual care at WakeMed pediatric clinic. The study will assess the impact of maternal stress and early life adversity on children's long-term health outcomes, particularly focusing on telomere length and epigenetic aging. The trial seeks to determine if improving caregiver sensitivity can mitigate the effects of stress on infants.
Why it matters
Potential benefit: If successful, this intervention could enhance maternal sensitivity and improve the long-term health of infants from under-resourced families.
How similar studies have gone: Other studies have shown promise in using parenting interventions to improve child health outcomes, suggesting this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Biological mother of infant aged 3-12 months English- or Spanish-speaking Receiving Medicaid Their infant is receiving pediatric care at WakeMed Exclusion Criteria: * Experiencing an acute crisis (e.g. hospitalization, incarceration) Homeless or without stable enough housing for home visits Lacking access to a phone Previously received the Promoting First Relationships intervention
Where it's running
-
WakeMed Health & Hospitals
Raleigh, North Carolina, United States Recruiting
Study contacts
- Principal investigator: Monica Oxford, PhD — University of Washington
- Study coordinator: Monica Oxford, PhD
- Email: mloxford@uw.edu
- Phone: 206-685-6107
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.