ImmunoPET imaging for pancreatic cancer
Official title: Development and Clinical Translation of immunoPET Imaging Probes for Pancreatic Cancer
Run by RenJi Hospital · NCT06602037 · Data updated 2026-11-12
This study is testing a new imaging method to see how well a targeted therapy for pancreatic cancer gets taken up by tumors and healthy tissues in patients with pancreatic cancer.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | RenJi Hospital Academic / other |
| Locations | 1 site (Shanghai) |
| Status | Recruiting |
| Started | November 20, 2024 |
| Main results expected | June 2027 |
| Study ends | June 2027 |
| Registry record updated | December 29, 2025 |
| Trial ID | NCT06602037 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals with histologically confirmed or suspected pancreatic cancer who can provide informed consent.
✕Probably not a fit
Patients with known hypersensitivity to the study agents or those who are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on using ImmunoPET imaging to evaluate the distribution of a targeted therapy for pancreatic cancer. Patients with confirmed or suspected pancreatic cancer will receive a radiolabeled antibody, SHR1920, which will be tracked using PET scans to assess its uptake in tumors and normal tissues. The study aims to determine the diagnostic efficacy of this imaging technique and its correlation with protein expression levels in tumors. By identifying patients who are more likely to benefit from targeted therapies, the study seeks to enhance treatment outcomes for pancreatic cancer.
Why it matters
Potential benefit: If successful, this approach could lead to more effective targeted therapies for patients with pancreatic cancer.
How similar studies have gone: While the use of ImmunoPET imaging is a novel approach in this context, similar imaging techniques have shown promise in other cancer types.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Histologically confirmed diagnosis of pancreatic cancer or suspected pancreatic cancer by diagnostic imaging. * Capable of giving signed informed consent which includes compliance with the requirements and restrictions listed in the informed consent form (ICF) and in this protocol. Exclusion Criteria: * Known or suspected hypersensitivity to SHR1920, DFO/RESCA/NOTA, 89Zr/18F or 68Ga or any of the excipients. * Pregnancy
Where it's running
-
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, China Recruiting
Study contacts
- Principal investigator: Weijun Wei, Ph.D. & M.D. — Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University
- Study coordinator: Weijun Wei, Ph.D. & M.D.
- Email: wwei@shsmu.edu.cn
- Phone: 15000083153
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.