Immediate upper-front tooth implants with bone augmentation, with or without a connective tissue graft

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will enroll patients needing an immediate single-tooth implant in the maxillary esthetic zone and randomly assign them to receive either bone augmentation alone or bone augmentation plus a connective tissue graft (CTG). All participants will receive immediate implant placement with a requirement for adequate primary stability, and clinicians will collect esthetic, clinical, and radiographic outcome measures. Follow-up visits will include esthetic scoring, soft-tissue and implant examinations, and radiographic assessment of bone levels over the healing period. The goal is to determine whether adding CTG leads to superior soft-tissue contour and long-term esthetic stability compared with bone grafting alone.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with a non-restorable tooth or a remaining root without signs of acute infection in the maxillary esthetic zone.
* The failing tooth is an incisor, canine or first bicuspid in the maxilla bounded by natural sound teeth.
* Sufficient bone (\>4 mm) apically and palatally to allow for proper implant positioning with sufficient primary stability (≥35 N cm).
* Sufficient mesial-distal and interocclusal space for placement of the implant and definitive restoration.

Exclusion Criteria:

* Patients with systemic conditions affecting bone healing (e.g., uncontrolled diabetes).
* Teeth with current acute periapical infection.
* Dehiscence of the labial (facial) bone plate after extraction.
* Signs of uncontrolled periodontal disease.
* Heavy smokers and vulnerable groups (pregnant females and decision-impaired individuals).
* History of head and neck radiation therapy.

Where it's running

• University of Baghdad/ College of Dentistry/ Department of Oral and Maxillofacial surgery/ Implant Unit
  Baghdad, Rusafa, Iraq Recruiting

Study contacts

• Study coordinator: Khalid Khalid, Bachelor of Dental Surgery
• Email: khaled.waleed2408m@codental.uobaghdad.edu.iq
• Phone: +9647716641706

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.