Imaging techniques to improve treatment of heart rhythm disorders
Official title: Peri-Procedural Transmural Electrophysiological Imaging of Scar-Related Ventricular Tachycardia
Run by Nova Scotia Health Authority · NCT03713866 · Data updated 2026-11-12
This study is testing if advanced imaging techniques can help doctors better treat heart rhythm problems in patients who have had a heart attack.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 85 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Nova Scotia Health Authority Academic / other |
| Locations | 1 site (Halifax, Nova Scotia) |
| Status | Recruiting |
| Started | November 1, 2019 |
| Main results expected | December 31, 2026 |
| Study ends | March 31, 2027 |
| Registry record updated | March 17, 2026 |
| Trial ID | NCT03713866 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with a history of sustained monomorphic ventricular tachycardia who have been referred for catheter ablation and have a previously implanted ICD.
✕Probably not a fit
Patients with severe renal impairment, life expectancy under six months, or contraindications to catheter ablation will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the use of advanced imaging techniques to enhance the treatment of ventricular tachycardia (VT) in patients with myocardial infarction. It aims to integrate functional VT data with 3D imaging from CT or MRI to better visualize the electrical circuits involved in VT. A total of 40 patients referred for catheter ablation will undergo noninvasive imaging and stimulation studies before and after the ablation procedure. The goal is to improve the identification of ablation targets and assess the outcomes of the treatment.
Why it matters
Potential benefit: If successful, this approach could lead to more effective ablation procedures and improved outcomes for patients with scar-related ventricular tachycardia.
How similar studies have gone: Other studies have shown promise in using advanced imaging techniques for cardiac conditions, suggesting potential success for this novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * One or more episodes of sustained monomorphic VT * Referred for catheter ablation * Previously implanted ICD * Signed the patient informed consent form * Able and willing to comply with all pre-, post-, and follow-up testing and requirements Exclusion Criteria: * Have estimated Glomerular Filtration Ratio (eGFR) less than 30 * Have a life expectancy less than 6 months or are listed for heart transplantation at time of inclusion * Are pregnant * Are on IV inotropic agents * Have any contraindication to catheter ablation (including but not limited to mechanical prosthetic aortic and mitral valves, known protruding Left Ventricular (LV) thrombus * New York Heart Association (NYHA) functional class IV * Had ST wave elevation myocardial infarction within \< 1 month * Unwilling or unable to undergo cardiac MRI scan AND unwilling or unable to undergo cardiac CT scan (e.g. contrast allergy).
Where it's running
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Qeii Hsc
Halifax, Nova Scotia, Canada Recruiting
Study contacts
- Principal investigator: John L Sapp, MD FRCPC — Nova Scotia Health Authority
- Study coordinator: John L Sapp, MD FRCPC
- Email: john.sapp@nshealth.ca
- Phone: 902 473 4272
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Using SBRT to treat ventricular tachycardia
This study is testing if a special type of radiation therapy can help patients with ventricular tachycardia who haven't found relief from other treatments.
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Heart@Home: Safe, at-home care for people with acute heart problems compared with hospital care
This trial tests whether hospital-level care at home can safely and effectively treat adults with acute heart conditions who would normally be in the hospital.
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Digital cardiac rehab to help heart attack patients improve function
A digital health–supported cardiac rehabilitation program is being tested to see if it helps people after a heart attack improve fitness and stay engaged with rehab, compared with standard outpatient rehab.
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AI-powered ECG to help diagnose and locate tachycardia in patients with PSVT, WPW, PVC, or VT
A multicenter registry test whether an AI-enabled ECG analysis can help diagnose and localize tachycardia in adults with certain arrhythmias.
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NMR-based Risk Test and Digital Health Support for midlife adults in Eloisa
This study tests whether an NMR metabolomics risk test can guide tailored digital health programs for midlife adults at risk of diabetes, heart disease, stroke, kidney disease, or fatty liver.
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See if stopping long-term aspirin is as good as continuing it in older adults with stable ischemic heart disease
In adults 65 and older with stable ischemic heart disease, this trial tests whether stopping daily low-dose aspirin is not worse than continuing it.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.