Imaging active blood clots using PET technology
Official title: Molecular Imaging of Active Venous Thrombus With Positron Emission Tomography (PET)
Run by University Hospital, Brest · NCT06057844 · Data updated 2026-11-12
This study is testing a new way to use PET scans to see active blood clots in people with conditions like deep vein thrombosis and pulmonary embolism, to help doctors decide who really needs blood-thinning treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10 (estimated) |
| Sponsor | University Hospital, Brest Academic / other |
| Locations | 1 site (Brest) |
| Status | Recruiting |
| Started | February 27, 2024 |
| Main results expected | August 28, 2026 |
| Study ends | August 28, 2026 |
| Registry record updated | June 8, 2026 |
| Trial ID | NCT06057844 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who are voluntary blood donors without significant medical histories affecting coagulation.
✕Probably not a fit
Patients under 18 years old, those with chronic health issues, or those currently on anticoagulant or anti-platelet therapies may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to improve the diagnostic accuracy of venous thromboembolism (VTE), which includes conditions like deep vein thrombosis and pulmonary embolism. It focuses on utilizing positron emission tomography (PET) to visualize active venous thrombi directly, contrasting with traditional imaging techniques that only show the effects of obstructions. By marking the thrombus, the study seeks to better identify patients who require anticoagulant treatment and avoid unnecessary long-term therapy for those who do not. The approach involves additional blood sampling to enhance the imaging process.
Why it matters
Potential benefit: If successful, this study could lead to more accurate diagnoses of VTE, ensuring appropriate treatment for patients and reducing unnecessary medication.
How similar studies have gone: While traditional imaging techniques are well-established, this novel approach using PET for direct thrombus visualization has not been widely tested, making it a potentially groundbreaking method.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Major patient (≥18 years), voluntary blood donor, with no notable medical history altering coagulation (i.e. known thrombophilia, active cancer), no chronic pathology, no current treatment. Exclusion Criteria: Minor patient (\<18 years); known chronic pathology; long-term treatment including anti-platelet aggregation therapy or anticoagulant treatment, refusal to participate.
Where it's running
-
Etablissement francais du sang
Brest, France Recruiting
Study contacts
- Study coordinator: Philippe ROBIN
- Email: philippe.robin@chu-brest.fr
- Phone: +33(0)298223327
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.