Identifying triggers of IBD flare-ups
Microbial and Human Determinants of the Onset of IBD Flares
This study is trying to find out what causes flare-ups in people with Inflammatory Bowel Disease by looking at their samples and surveys to help improve treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Viome Industry-sponsored |
| Locations | 1 site (Florianópolis, Santa Catarina) |
| Trial ID | NCT06967311 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect longitudinal biological samples and survey data from patients with Inflammatory Bowel Disease (IBD) to identify the microbial and human molecular triggers of IBD relapses. The study will explore microbial and human pathways associated with flares that could be targeted for nutritional interventions with therapeutic potential. Additionally, it seeks to identify biomarkers for diagnosing IBD and to understand microbial functions related to the release of BH4.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with IBD who are receiving care at the Universidade Federal de Santa Catarina.
Not a fit: Patients with a current cancer diagnosis or those under 18 years old may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better management strategies for IBD patients by identifying specific triggers and potential therapeutic targets.
How similar studies have performed: While there have been studies exploring the microbiome in relation to IBD, this specific approach focusing on longitudinal triggers is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient at Universidade Federal de Santa Catarina (UFSC) Hospital, under care of Dr. Vivian Menegassi Exclusion Criteria: * Cancer Diagnosis/Treatment * Under 18 years old
Where this trial is running
Florianópolis, Santa Catarina
- LABOX, Department of Biochemistry, Universidade Federal de Santa Catarina — Florianópolis, Santa Catarina, Brazil (Recruiting)
Study contacts
- Study coordinator: Raquel Clinical Research Coordinator
- Email: studies@viome.com
- Phone: 425-368-5248
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.