Identifying tissue markers that predict early stenosis in AV fistulas for hemodialysis
Tissue Markers Predictive of Early Stenosis in the Arterovenous Fistula for Hemodialysis
This study is trying to find out if certain tissue markers can help predict early narrowing in arteriovenous fistulas for people starting hemodialysis.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna) |
| Trial ID | NCT06815159 on ClinicalTrials.gov |
What this trial studies
This study recruits two groups of patients undergoing surgery for arteriovenous fistulas (AVF) for hemodialysis. The first group consists of patients undergoing their first AVF surgery, while the second group includes patients reoperated for complications or new AVF creation. Tissue samples will be collected from both groups and analyzed for markers that may indicate early stenosis. The study aims to explore the relationship between these tissue markers and the occurrence of stenosis in AVFs.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are undergoing their first AVF surgery or reoperation for AVF complications.
Not a fit: Patients who are not candidates for AVF surgery or those with contraindications to the procedure may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved predictive measures for early stenosis in AV fistulas, enhancing patient outcomes in hemodialysis.
How similar studies have performed: While the approach of identifying tissue markers is common, the specific focus on early stenosis in AV fistulas is relatively novel and has not been extensively tested in previous studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age greater than or equal to 18 years; * Patients candidates for first AVF for hemodialysis or correction of AVF complication, as part of the normal care pathway; * Obtaining informed consent signed by the patient Exclusion Criteria:
Where this trial is running
Bologna
- IRCCS AOU di Bologna Policlinico di Sant'Orsola — Bologna, Italy (Recruiting)
Study contacts
- Principal investigator: Mauro Gargiulo, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Mauro Gargiulo, MD
- Email: mauro.gargiulo2@unibo.it
- Phone: 0512143288
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.