Identifying seizure events through breath and sweat analysis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect breath and sweat samples from patients admitted to hospitals after experiencing potential seizures. The researchers will analyze these samples to identify patterns of small molecules that can differentiate between epileptic seizures and other events, potentially determining the severity of the seizure. By developing a non-invasive 'seizure test', the study seeks to improve diagnostic accuracy for patients experiencing seizure-like events.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients who have been admitted to either University College London's Queen's Square EEG-telemetry unit or Chalfont Centre for Epilepsy, for diagnosis of seizure events.
2. Patients aged 18 years or above

Exclusion Criteria:

1. Patients with active infection or who have taken antibiotics within 4 weeks
2. Patients on immunosuppressive medications
3. Patients with co-morbidities preventing breath collection
4. Patients unable to provide informed consent.

Where it's running

• Chalfont Centre for Epilepsy
  London, Buckinghamshire, United Kingdom Recruiting
• National Hospital for Neurology and Neurosurgery
  London, London, United Kingdom Recruiting

Study contacts

• Principal investigator: Matthew Walker, MB BChir FRCP — Professor
• Study coordinator: Eleonora Lugara, PhD
• Email: e.lugara@ucl.ac.uk
• Phone: 02031089108

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.