Identifying risk factors for gastric cancer in a Hispanic population
Identification of Molecular and Epidemiological Risk Factors in the Development of Gastric Cancer in High-risk Predominantly Hispanic Population
This study looks at what causes gastric cancer in Hispanic people in South Texas by testing tissue samples and gathering information about known risk factors to help improve prevention and treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | The University of Texas Health Science Center at San Antonio Academic / other |
| Locations | 1 site (San Antonio, Texas) |
| Trial ID | NCT04600466 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify molecular and epidemiological risk factors associated with gastric cancer in a high-risk Hispanic population in South Texas. It consists of two main parts: the first part involves molecular testing on tissue samples from patients with gastric adenocarcinoma to identify differences between Hispanic and Non-Hispanic patients, while the second part includes surveys and testing for known risk factors like Helicobacter pylori and Epstein-Barr virus. The study seeks to correlate these findings to better understand the unique risk factors for gastric cancer in this demographic. Ultimately, the goal is to improve prevention and treatment strategies for gastric cancer.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with a histologically confirmed diagnosis of gastric adenocarcinoma.
Not a fit: Patients with well-established hereditary cancer syndromes or those with certain types of gastroesophageal junction adenocarcinoma may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention and surveillance strategies for gastric cancer in high-risk populations.
How similar studies have performed: While there have been studies on gastric cancer risk factors, this specific focus on the Hispanic population in South Texas is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18 years or older * Patient with histologically confirmed diagnosis of gastric adenocarcinoma * Able to understand English or Spanish (only for the prospective cohort) * GEJ adenocarcinoma Type II (within 1 cm above and 2 cm below the GEJ) and Type III (2-5 cm below the GEJ) * Hyperplastic polyps Exclusion Criteria: * Clinically AND genetically confirmed diagnosis of well-established hereditary cancer syndrome * Gastroesophageal junction (GEJ) adenocarcinoma Type I (1-5 cm above the GEJ) as they are treated as esophageal cancer * Other benign or malignant histology types (i.e. leiomyoma, gastrointestinal stroma tumors, fundic gland polyps, etc.)
Where this trial is running
San Antonio, Texas
- Mays Cancer Center, UT Health San Antonio — San Antonio, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Mio Kitano, MD — University of Texas Health Science Center San Antonio
- Study coordinator: Mio Kitano, MD
- Email: KITANO@UTHSCSA.EDU
- Phone: 210-450-5990
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.