Identifying risk factors for cognitive issues in elderly patients undergoing surgery
Biomarkers and Risk Factors for Perioperative Neurocognitive Disorders in Elderly Non-neurosurgical Patients
This study is trying to find out what factors might lead to memory and thinking problems in older patients who are having surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Jinan Central Hospital Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT06044207 on ClinicalTrials.gov |
What this trial studies
This observational study collects basic information and biological samples from elderly patients before and during surgery to investigate the risk factors and biomarkers associated with perioperative neurocognitive dysfunction. Patients are assessed for cognitive function postoperatively and categorized into case and control groups based on their cognitive performance. The study employs various psychological assessments, including the Pittsburgh Sleep Quality Index and the Montreal Cognitive Assessment, to gather comprehensive data on cognitive health. Statistical analysis will be used to derive insights from the collected data.
Who should consider this trial
Good fit: Ideal candidates for this study are elderly patients aged 65 and older who are classified as ASA grade I to III.
Not a fit: Patients with a history of craniocerebral surgery or trauma, or those unable to complete psychological assessments, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for preventing cognitive dysfunction in elderly surgical patients.
How similar studies have performed: Other studies have shown success in identifying cognitive dysfunction risk factors in surgical patients, suggesting this approach has potential.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age more than or equal to 65 years old * ASA classification Ⅰ\~Ⅲ grade Exclusion Criteria: * History of previous Craniocerebral surgery or Craniocerebral trauma * Inability to successfully complete preoperative psychological function tests * Those who are severely deaf, speech impaired and otherwise unable to communicate.
Where this trial is running
Jinan, Shandong
- Jinan Central Hospital — Jinan, Shandong, China (Recruiting)
Study contacts
- Study coordinator: Wenying Chi, Master
- Email: cwy2907@zxyy.cn
- Phone: 18654557772
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.