Identifying Risk Factors for Cancer in Patients with Type 2 Diabetes

Type 2 Diabetes Mellitus and Cancer: Phenotyping of Patients at a Third-level Diabetes Centre

Observational Azienda Ospedaliero Universitaria Maggiore della Carita · NCT06299800

This study looks at how type 2 diabetes might be linked to cancer by checking what factors could increase the risk for patients who had diabetes between 1990 and 2010.

Quick facts

Study typeObservational
Enrollment779 (estimated)
Ages18 Years and up
SexAll
SponsorAzienda Ospedaliero Universitaria Maggiore della Carita Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Novara)
Trial IDNCT06299800 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the relationship between type 2 diabetes mellitus and cancer by identifying risk factors that may influence tumor development and progression. It will utilize a monocentric retrospective cohort design, analyzing data from patients diagnosed with type 2 diabetes at the Endocrinology and Diabetology surgery of the AOU Major of the Charity of Novara between 1990 and 2010. The study will track the onset of cancer in these patients and assess the time interval between their diabetes diagnosis and cancer occurrence. This information is crucial for developing effective preventive strategies in clinical practice.

Who should consider this trial

Good fit: Ideal candidates for this study are adults diagnosed with type 2 diabetes mellitus between 1990 and 2010.

Not a fit: Patients who were diagnosed with cancer prior to their diabetes diagnosis or have diabetes secondary to other conditions or treatments may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved preventive measures and treatment strategies for patients with type 2 diabetes at risk of developing cancer.

How similar studies have performed: While the relationship between diabetes and cancer has been explored in various studies, this specific approach of phenotyping patients in a retrospective cohort setting is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Legal age
* Diagnosis of type 2 diabetes mellitus

Exclusion Criteria:

* Diagnosis of cancer before diagnosis of type 2 diabetes
* Diagnosis of diabetes secondary to other diseases
* Diagnosis of diabetes secondary to other drugs
* Diagnosis of diabetes following surgery

Where this trial is running

Novara

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Diabetes Mellitus, Type 2Cancercancerdiabetes mellitus type 2
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.