Identifying predictors of arm recovery after stroke rehabilitation
Investigation of Neurophysiological Substrates and Clinical Behaviour for Prognosis of Rehabilitation-induced Upper Limb Recovery After Stroke: Longitudinal Cohort Study
IRCCS San Camillo, Venezia, Italy · NCT05423119
This study is trying to find out what factors can help predict how well stroke patients will recover their arm function during rehabilitation.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 75 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS San Camillo, Venezia, Italy (other) |
| Locations | 1 site (Lido, Venezia) |
| Trial ID | NCT05423119 on ClinicalTrials.gov |
What this trial studies
This observational cohort study aims to identify clinical predictors of arm recovery in stroke patients undergoing rehabilitation. It will assess neurophysiological and behavioral features, including the integrity of the Cortico-Spinal Tract and Motor Evoked Potentials, to determine their impact on recovery outcomes. Patients will be evaluated at the start of rehabilitation and after eight weeks using Magnetic Resonance Imaging, Transcranial Magnetic Stimulation, blood samples, and clinical outcome measures. The study will also explore how the dosage of rehabilitation therapy influences recovery.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals who have experienced their first unilateral cortical or subcortical stroke.
Not a fit: Patients with other neurological diseases, psychiatric disorders, or cerebellar strokes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into predicting arm recovery in stroke patients, leading to more personalized rehabilitation strategies.
How similar studies have performed: While there is existing literature on spontaneous recovery after stroke, this study's focus on rehabilitation-induced recovery predictors is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * first ever single stroke * unilateral cortical/subcortical stroke Exclusion Criteria: * other neurological disease * psychiatric disorders * cerebellar stroke
Where this trial is running
Lido, Venezia
- IRCCSSanCamillo — Lido, Venezia, Italy (RECRUITING)
Study contacts
- Principal investigator: Nicola Filippiin — IRCCS San Camillo, Venezia, Italy
- Study coordinator: Nicola Filippini, PhD
- Email: nicola.filippini@hsancamillo.it
- Phone: +39 0412207435
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Stroke, rehabilitation, upper limb, prognosis, neurophysiology