Identifying optimal brain blood pressure after surgery
Research and Development of Innovative Method and Technology for Cerebral Perfusion Pressure Diagnosis
This study is trying to find the best blood pressure levels for patients recovering from brain surgery to help improve their recovery and outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Vilnius University Academic / other |
| Locations | 1 site (Vilnius) |
| Trial ID | NCT06028906 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate how quickly optimal cerebral perfusion pressure (optCPP) and optimal arterial blood pressure (optABP) can be identified in intensive care patients following brain surgery. By monitoring various physiological parameters, including arterial blood pressure and intracranial pressure, the study seeks to develop an algorithm that can determine the optimal brain perfusion pressure within a short time frame. The research will involve both prospective data collection and retrospective analysis of clinical monitoring data to understand the dynamics of cerebral autoregulation in response to changing blood pressure. The ultimate goal is to enhance patient outcomes by ensuring timely management of cerebral perfusion.
Who should consider this trial
Good fit: Ideal candidates for this study are patients who have suffered traumatic brain injuries or subarachnoid hemorrhages.
Not a fit: Patients with mental disorders, minors, or those currently in care institutions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management of brain perfusion in critically ill patients, potentially reducing complications and enhancing recovery.
How similar studies have performed: While the approach of monitoring cerebral perfusion pressure is established, the specific method of rapid identification being tested in this study is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Traumatic brain injury patients * Subarachnoid hemorrhage patients Exclusion Criteria: * persons with mental disorders, but who can give consent to participate in biomedical research; * minors; * students, if their participation in biomedical research is related to studies; * persons living in care institutions; * soldiers during their actual military service; * employees of health care institutions where biomedical research is conducted, subordinate to the researcher;
Where this trial is running
Vilnius
- Vilnius University Hospital Santaros klinikos — Vilnius, Lithuania (Recruiting)
Study contacts
- Principal investigator: Saulius Rocka — Head of the Neurosurgery Center at Vilnius University Hospital Santaros klinikos
- Study coordinator: Saulius Rocka, Prof. Dr.
- Email: saulius.rocka@santa.lt
- Phone: +37068743480
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.