Identifying new markers to predict gestational diabetes and large babies.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate new glycation markers, specifically skin autofluorescence and glycated albumin, as predictors of gestational diabetes mellitus (GDM) and macrosomia in pregnant women. It compares these novel markers to the traditional HbA1c measurement to determine their effectiveness in identifying risks for adverse pregnancy outcomes. The study will involve pregnant women who are less than 28 weeks into their pregnancy and will assess their glycation levels to improve screening strategies for GDM. The goal is to enhance early detection and management of these conditions.

Why it matters

Who can join: the full rules

Inclusion criteria:

1. Age ≥ 18 years
2. Singleton pregnancy (or twin pregnancy reduced spontaneously or medically before 14 weeks of amenorrhea)
3. Gestational age at inclusion \<28 weeks of amenorrhea
4. Participant affiliated with or beneficiary of a social security scheme
5. Collection of patient consent.

Exclusion criteria:

1. Gestational age at inclusion ≥ 28 weeks of amenorrhea
2. Multiple pregnancy
3. Known diabetes prior to pregnancy
4. History of bariatric surgery
5. Expected delivery in another maternity unit not participating in the study
6. Person deprived of liberty by judicial or administrative decision
7. Guardianship or curatorship
8. Participant not affiliated or not benefiting from a social security scheme.

Where it's running

• Hopital Pellegrin
  Bordeaux, France Recruiting

Study contacts

• Study coordinator: FOUSSARD NINON, Dr
• Email: ninon.foussard@u-bordeaux.fr
• Phone: 5.57.65.60.78

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Behavioral toolkit to help pregnant women manage gestational diabetes and pregnancy-related high blood pressure.

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• Early pregnancy lifestyle patterns and glucose changes in a TOFFFY sub-study

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• Using a 24-hour continuous glucose monitor after delivery to predict future Type 2 diabetes risk in people with gestational diabetes

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• Continuous glucose monitoring to find and manage early high blood sugar in pregnancy

  This uses continuous glucose monitors in early pregnancy for people without diabetes to find and treat high blood sugar and try to reduce problems for mother and baby.

  Recruiting at 8 sites Jaeb Center for Health Research · Birmingham, Alabama and 9 other locations · NCT06957028

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.