Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Identifying metabolic markers for preventing atrial fibrillation

Official title: Identification of the Metabolic Signature of Atrial Fibrillation for Personalized Prevention

Run by University Hospital, Bordeaux · NCT06735001 · Data updated 2026-11-12

This study is trying to find specific metabolic markers in patients having heart surgery to see if they can help predict and prevent the return of atrial fibrillation.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment400 (estimated)
SponsorUniversity Hospital, Bordeaux
Academic / other
Locations1 site (Pessac)
StatusRecruiting
StartedMarch 10, 2025
Main results expectedOctober 2029
Study endsOctober 2029
Registry record updatedJune 9, 2026
Trial IDNCT06735001 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who are scheduled for cardiac ablation due to atrial fibrillation.

Probably not a fit

Patients under 18, those with active tumors, or individuals with certain chronic diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to identify metabolic and biomolecular signatures associated with atrial fibrillation (AF) in patients scheduled for cardiac ablation. By monitoring these signatures over a 12-month period, the research seeks to develop a method for assessing the risk of AF recurrence. The approach combines traditional risk factors with metabolic biomarkers using machine learning techniques to enhance personalized prevention strategies. The ultimate goal is to improve outcomes for patients at risk of AF by providing tailored interventions.

Why it matters

Potential benefit: If successful, this study could lead to personalized prevention strategies that significantly reduce the recurrence and progression of atrial fibrillation.

How similar studies have gone: While the approach of identifying metabolic signatures is innovative, similar studies have shown promise in other cardiovascular conditions, indicating potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years, all genders, and ethnic origins
* Free, informed, and written consent signed
* Person affiliated to or benefiting from a social security scheme

Exclusion Criteria:

* Age \< 18 years
* Lack of informed consent
* Gestating women (pregnancy test carried out as part of care for FA patients, contraception, or menopause for women in control groups)
* Persons under administrative or judicial protection
* Endocarditis or pericarditis in progress or within the 3 last months
* Active tumor pathology (benign or malignant)
* Chronic inflammation or autoimmune disease
* Chronic liver disease
* Myocardial infarction within the last 8 weeks

Where it's running

  • University Hospital of Bordeaux
    Pessac, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.