Clinical trial Recruiting at 7 sites Observational Ages 18 and up

Identifying markers to predict treatment response in pancreatic cancer patients

Official title: Prognostic and Predictive Markers of Treatment Response in Patients With Pancreatic Adenocarcinoma

Run by GERCOR - Multidisciplinary Oncology Cooperative Group · NCT05776342 · Data updated 2026-11-12

This study is trying to find markers that can help doctors predict how well different treatments will work for people with pancreatic cancer.

More Pancreatic Adenocarcinoma trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment4050 (estimated)
SponsorGERCOR - Multidisciplinary Oncology Cooperative Group
Academic / other
Drugs / interventionschemotherapy
Locations15 sites (Besançon and 14 other locations)
StatusRecruiting
StartedJanuary 1, 2003
Main results expectedDecember 31, 2030
Study endsDecember 31, 2031
Registry record updatedMarch 25, 2025
Trial IDNCT05776342 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older with histologically confirmed pancreatic adenocarcinoma at various stages of the disease.

Probably not a fit

Patients who are under guardianship, pregnant, breastfeeding, or unable to comply with the study protocol may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify prognostic and predictive markers that can help determine how patients with pancreatic adenocarcinoma respond to various treatments, including surgery and chemotherapy. By analyzing a multicenter cohort derived from current clinical practice, the study seeks to evaluate the effectiveness and tolerance of these treatments. The goal is to develop tools that can stratify patients based on their estimated survival, thereby guiding therapeutic decisions and optimizing patient selection for future clinical trials.

Why it matters

Potential benefit: If successful, this study could lead to more personalized treatment plans for pancreatic cancer patients, improving their outcomes.

How similar studies have gone: Other studies have shown promise in identifying prognostic markers in pancreatic cancer, suggesting that this approach could yield valuable insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient with histologically confirmed pancreatic adenocarcinoma.
* Disease at a resectable, borderline, locally advanced, initially metastatic, or recurrent stage after surgery
* Diagnosis between January 1, 2003, and December 31, 2030.
* First-line treatment with chemotherapy and/or radiotherapy and/or clinical trials.
* Age ≥ 18 years.
* Written informed consent

Exclusion Criteria:

* Patient under guardianship, curatorship, or judicial protection.
* Pregnant or breastfeeding women.
* Any medical, psychological, or social situation that could prevent compliance with the protocol as assessed by the investigator.
* Refusal to participate in the study

Where it's running

  • CHU Jean Minjoz
    Besançon, France
    Recruiting
  • Hôpital Beaujon
    Clichy, France
    Recruiting
  • CHU Lille
    Lille, France
    Recruiting
  • HRU Nancy Site Brabois
    Nancy, France
    Recruiting
  • Hôpital Georges Pompidou
    Paris, France
    Recruiting
  • Hôpital Saint Antoine
    Paris, France
    Recruiting
Show 9 more locations
  • Hôpital Paul Brousse
    Villejuif, France
    Recruiting
  • CHU - Henri Mondor
    Créteil, France
    Not yet recruiting
  • Centre Léon Bérard
    Lyon, France
    Not yet recruiting
  • Institut Mutualiste Montsouris
    Paris, France
    Not yet recruiting
  • CHU Poitiers
    Poitiers, France
    Not yet recruiting
  • CHU Reims
    Reims, France
    Not yet recruiting
  • CHU Pontchaillou
    Rennes, France
    Not yet recruiting
  • Institut Curie
    Saint-Cloud, France
    Not yet recruiting
  • IHU - Institut de chirurgie guidée par l'imagerie
    Strasbourg, France
    Not yet recruiting

Study contacts

  • Principal investigator: Angelique VIENOT, MD — CHRU de Besançon - Institut Régional Fédératif du Cancer (IRFC) de Franche-Comté
  • Study coordinator: Angelique VIENOT, MD
  • Email: regulatory.Affairs@gercor.com.fr
  • Phone: 01402985 00

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.