Identifying markers to predict treatment response in pancreatic cancer patients
Official title: Prognostic and Predictive Markers of Treatment Response in Patients With Pancreatic Adenocarcinoma
Run by GERCOR - Multidisciplinary Oncology Cooperative Group · NCT05776342 · Data updated 2026-11-12
This study is trying to find markers that can help doctors predict how well different treatments will work for people with pancreatic cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 4050 (estimated) |
| Sponsor | GERCOR - Multidisciplinary Oncology Cooperative Group Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 15 sites (Besançon and 14 other locations) |
| Status | Recruiting |
| Started | January 1, 2003 |
| Main results expected | December 31, 2030 |
| Study ends | December 31, 2031 |
| Registry record updated | March 25, 2025 |
| Trial ID | NCT05776342 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older with histologically confirmed pancreatic adenocarcinoma at various stages of the disease.
✕Probably not a fit
Patients who are under guardianship, pregnant, breastfeeding, or unable to comply with the study protocol may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to identify prognostic and predictive markers that can help determine how patients with pancreatic adenocarcinoma respond to various treatments, including surgery and chemotherapy. By analyzing a multicenter cohort derived from current clinical practice, the study seeks to evaluate the effectiveness and tolerance of these treatments. The goal is to develop tools that can stratify patients based on their estimated survival, thereby guiding therapeutic decisions and optimizing patient selection for future clinical trials.
Why it matters
Potential benefit: If successful, this study could lead to more personalized treatment plans for pancreatic cancer patients, improving their outcomes.
How similar studies have gone: Other studies have shown promise in identifying prognostic markers in pancreatic cancer, suggesting that this approach could yield valuable insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient with histologically confirmed pancreatic adenocarcinoma. * Disease at a resectable, borderline, locally advanced, initially metastatic, or recurrent stage after surgery * Diagnosis between January 1, 2003, and December 31, 2030. * First-line treatment with chemotherapy and/or radiotherapy and/or clinical trials. * Age ≥ 18 years. * Written informed consent Exclusion Criteria: * Patient under guardianship, curatorship, or judicial protection. * Pregnant or breastfeeding women. * Any medical, psychological, or social situation that could prevent compliance with the protocol as assessed by the investigator. * Refusal to participate in the study
Where it's running
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CHU Jean Minjoz
Besançon, France Recruiting -
Hôpital Beaujon
Clichy, France Recruiting -
CHU Lille
Lille, France Recruiting -
HRU Nancy Site Brabois
Nancy, France Recruiting -
Hôpital Georges Pompidou
Paris, France Recruiting -
Hôpital Saint Antoine
Paris, France Recruiting
Show 9 more locations
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Hôpital Paul Brousse
Villejuif, France Recruiting -
CHU - Henri Mondor
Créteil, France Not yet recruiting -
Centre Léon Bérard
Lyon, France Not yet recruiting -
Institut Mutualiste Montsouris
Paris, France Not yet recruiting -
CHU Poitiers
Poitiers, France Not yet recruiting -
CHU Reims
Reims, France Not yet recruiting -
CHU Pontchaillou
Rennes, France Not yet recruiting -
Institut Curie
Saint-Cloud, France Not yet recruiting -
IHU - Institut de chirurgie guidée par l'imagerie
Strasbourg, France Not yet recruiting
Study contacts
- Principal investigator: Angelique VIENOT, MD — CHRU de Besançon - Institut Régional Fédératif du Cancer (IRFC) de Franche-Comté
- Study coordinator: Angelique VIENOT, MD
- Email: regulatory.Affairs@gercor.com.fr
- Phone: 01402985 00
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.