Clinical trial Recruiting at 1 site Observational Ages 20 to 40 Women only

Identifying markers for endometrial receptivity during pregnancy

Official title: Transcriptome Profiling and Immune/ Biochemical Markers of Peripheral Blood to Predict Endometrial Receptivity and Successful Implantation

Run by Chinese University of Hong Kong · NCT03925311 · Data updated 2026-11-12

This study is trying to find out if certain biological markers can help predict the best time for a fertilized egg to implant in the uterus during pregnancy for women aged 20-40.

Quick facts

Study typeObservational
Ages20 Years to 40 Years
SexWomen only
Enrollment220 (estimated)
SponsorChinese University of Hong Kong
Academic / other
Locations1 site (Hong Kong)
StatusRecruiting
StartedApril 20, 2015
Main results expectedDecember 31, 2025
Study endsDecember 31, 2025
Registry record updatedMarch 27, 2025
Trial IDNCT03925311 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are women aged 20-40 who are trying to conceive and have no significant uterine anomalies.

Probably not a fit

Patients with uncorrected uterine anomalies, intrauterine adhesions, or adenomyosis may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify and correlate biochemical markers that reflect the window of implantation (WOI) during the midluteal phase of the menstrual cycle. Participants aged 20-40 will undergo endometrial biopsy and blood sampling at specific time points, including pre-conception and during pregnancy. The goal is to establish reliable clinical and biochemical indicators of WOI, which is crucial for successful implantation and pregnancy outcomes.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and identification of optimal conditions for implantation, potentially enhancing pregnancy rates.

How similar studies have gone: While there have been studies exploring endometrial receptivity, this specific approach of correlating biochemical markers with WOI is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Age 20-40 years.

Exclusion Criteria:

* Uncorrected uterine anomalies, such as septate or bicornuate uterus, fibroids (submucous/intramural).
* Intrauterine adhesions.
* Adenomyosis.

Where it's running

  • Chinese University of Hong Kong
    Hong Kong, Hong Kong
    Recruiting

Study contacts

  • Principal investigator: Pui Wah Jacqueline Chung, MBBS — Chinese University of Hong Kong
  • Study coordinator: Hiu Tan Margaret Lee
  • Email: margaretlee@cuhk.edu.hk
  • Phone: 85235051764

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.