Identifying Health Markers to Reduce Complications in Spine Surgery

ORTHOSPINE FITNESS: Which Markers of Musculoskeletal Health Can Explain Complications in Spinal Surgery?

NA · Istituto Ortopedico Rizzoli · NCT06736106

This study is trying to find out if certain health markers can help predict and reduce complications for people having spine surgery for degenerative conditions.

Quick facts

PhaseNA
Study typeInterventional
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorIstituto Ortopedico Rizzoli (other)
Locations2 sites (Bologna and 1 other locations)
Trial IDNCT06736106 on ClinicalTrials.gov

What this trial studies

This study aims to investigate various markers of musculoskeletal health to understand their role in complications arising from spinal surgery for degenerative conditions. It involves a multicenter approach, utilizing advanced imaging techniques and assessments of physical fragility, muscle strength, and nutritional status in patients undergoing thoraco-lumbar spine surgery. The goal is to establish a comprehensive preoperative screening process that can enhance surgical decision-making and potentially reduce adverse outcomes. By identifying significant health markers, the study seeks to facilitate tailored preoperative interventions for better patient outcomes.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older with degenerative spinal conditions requiring surgical intervention.

Not a fit: Patients with tumors, infections in the spinal column, or those without surgical indications for their degenerative spine conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced complications for patients undergoing spinal surgery.

How similar studies have performed: While the approach of using comprehensive musculoskeletal health markers is innovative, similar studies have shown promise in improving surgical outcomes in other contexts.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \>= 18 years;
* diagnosis of degenerative pathology of the spinal column of the thoraco-lumbo-sacral tract;
* patients candidates for surgical treatment for the aforementioned pathology during the study period;
* willingness to participate in the study and sign the specific informed consent

Exclusion Criteria:

* presence of tumors or infections in the spinal column;
* presence of degenerative pathology of the spine without surgical indication;
* presence of degenerative pathology of the spinal column at the cervical level.

Where this trial is running

Bologna and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Spine Injuries and Disorders, spine surgery, muscle strength, physical fragility, musculoskeletal system, degenerative pathologies, thoraco-lumbar spine

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.