Identifying genetic factors in drug reactions in children and adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect DNA and plasma samples from children and adults who experience adverse drug reactions (ADRs) and those who do not. By comparing these samples, the study seeks to identify genetic differences that may contribute to ADRs and develop personalized drug dosing guidelines. The research will also analyze the use of medical services and vital statistics between participants with and without ADRs. The study will utilize a hospital-based active surveillance network across major hospitals in Canada to gather clinical material.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Children under 19 years who have taken drugs.
* Biological parents of children who have had an ADR.
* Patients/parents who speak and understand English (except in Quebec).
* Adults (for validation of findings in children)

Where it's running

• Children's and Women's Health Centre of British Columbia
  Vancouver, British Columbia, Canada Recruiting

Study contacts

• Principal investigator: Bruce Carleton, Pharm. D. — University of British Columbia
• Study coordinator: Bruce Carleton, PharmD.
• Email: bcarleton@popi.ubc.ca
• Phone: 604-875-2179

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.