Identifying factors that predict loss of autonomy in patients with memory disorders
Official title: Predictive Factors Associated With Impairment in Functional Autonomy in a Regional Real-life Cohort of Patients With Alzheimer's Disease or Related Disorders (ADRD)
Run by Hospices Civils de Lyon · NCT03894254 · Data updated 2026-11-12
This study is trying to find out what factors can help predict how changes in memory disorders affect daily life for people with Alzheimer's and similar conditions.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 5400 (estimated) |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 5 sites (Caluire-et-Cuire and 4 other locations) |
| Status | Recruiting |
| Started | September 9, 2020 |
| Main results expected | March 1, 2024 |
| Study ends | March 1, 2032 |
| Registry record updated | May 2, 2022 |
| Trial ID | NCT03894254 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients aged 18 and older with memory impairment who are undergoing medical visits in memory centers or neuro-cognition services.
✕Probably not a fit
Patients living in institutions or those with impairments that prevent examinations may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to develop a regional database to identify predictive factors associated with changes in functional autonomy levels in patients with Alzheimer's disease and related disorders. It will involve a cohort of approximately 5400 patients who will be monitored every 6 to 12 months across various centers in the Auvergne Rhone-Alpes region of France. The study will collect patient medical records on a prospective basis, collaborating with medical and administrative staff as well as university hospital computer science departments. The focus is on understanding the progression of cognitive impairment and its impact on daily functioning.
Why it matters
Potential benefit: If successful, this study could lead to better understanding and management of memory disorders, potentially improving patient care and outcomes.
How similar studies have gone: While similar studies have explored predictive factors in memory disorders, this specific approach of developing a regional database is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 years and older, undergoing a medical visit in a memory center or neuro-cognition service * Patients living at home or in housing * Patients with memory impairment, at all stage of the disease Exclusion Criteria: * Patients in institution * Patients under legal protection * Patients with a hearing or visual impairment, which prevents carrying out examinations
Where it's running
-
Hôpital Dugoujon
Caluire-et-Cuire, France Recruiting -
Centre Hospitalier Lyon Sud
Lyon, France Recruiting -
Service de neuro-cognition et neuro-ophtalmologie du Groupement Hospitalier Est
Lyon, France Recruiting -
CHU Saint-Etienne
Saint-Etienne, France Recruiting -
Centre Mémoire de Ressources et de Recherche de Lyon
Villeurbanne, France Recruiting
Study contacts
- Principal investigator: Pierre Krolak-Salmon, PhD — Centre Mémoire de Ressources et de Recherche
- Study coordinator: Pierre Krolak-Salmon, PhD
- Email: pierre.krolak-salmon@chu-lyon.fr
- Phone: 04 72 43 20 50
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.