Identifying factors in platinum resistance for ovarian cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective study aims to identify factors contributing to resistance against platinum-based chemotherapy in patients diagnosed with epithelial ovarian cancer at any stage. Participants will receive standard platinum-based chemotherapy while clinical, biological, epidemiological, and therapeutic data will be collected over a five-year period. Biological samples, including blood, tumor biopsies, and ascites, will be collected concurrently with standard care procedures, ensuring no additional invasive procedures are required. The study will help build a comprehensive database to better understand treatment resistance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥ 18 years old
2. Epithelial ovarian cancer at initial diagnosis (all stages)
3. Curative treatment (exeresis surgery) not yet initiated excepted neo-adjuvant treatment
4. Indication of platinum based-chemotherapy
5. Patient affiliated to the french social security system
6. Patient must provide written informed consent prior to inclusion in the study and any study-specific procedure

Exclusion Criteria:

1. Non-epithelial ovarian tumor, borderline ovarian tumor
2. Patient with recurrent disease
3. Exploratory surgery not performed at the "Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT-O)"
4. Pregnant or breastfeeding women
5. Any psychological, familial, geographical or sociological condition potentially preventing the medical follow-up and/or study procedures
6. Patient who has forfeited his/her freedom by administrative or legal award or who is under legal protection (curatorship and guardianship, protection of justice)

Where it's running

• Institut Universitaire du Cancer de Toulouse - Oncopole
  Toulouse, France Recruiting

Study contacts

• Study coordinator: Gwenaël FERRON
• Email: Ferron.Gwenael@iuct-oncopole.fr
• Phone: 05 31 15 53 55

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Dual-target CAR-NK Cells for Peritoneal Cancers of the Ovary, Fallopian Tube, or Pseudoperitoneal Disease

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• Dual-Target CAR-NK Cells for Recurrent or Refractory Epithelial Ovarian Cancer

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.