Identifying diagnostic criteria for Primary Failure of Eruption
Primary Failure of Eruption (PFE) : Highlighting of Clinical, Radiological and Genetic Diagnostic Criteria: Consequences on the Therapeutic Management
NA · University Hospital, Strasbourg, France · NCT03580785
This study is trying to find clear signs and tests for Primary Failure of Eruption to help doctors better understand and treat this condition.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 6 Years and up |
| Sex | All |
| Sponsor | University Hospital, Strasbourg, France (other) |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Strasbourg) |
| Trial ID | NCT03580785 on ClinicalTrials.gov |
What this trial studies
This study aims to establish clinical, radiological, and genetic diagnostic criteria for Primary Failure of Eruption (PFE). It will also explore genotype-phenotype correlations in both PTHR1 and non-PTHR1 forms of PFE, as well as analyze therapeutic failures associated with the condition. The methodology includes various imaging techniques such as panoramic radiography, teleradiography, intraoral X-rays, and CT scans, alongside genetic analysis to provide a comprehensive understanding of PFE.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals over 6 years old diagnosed with Primary Failure of Eruption.
Not a fit: Patients under 6 years old or those with endocrine pathologies that may interfere with dental eruption will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and therapeutic strategies for patients suffering from Primary Failure of Eruption.
How similar studies have performed: While there may be limited studies specifically targeting PFE, the approach of combining genetic and radiological assessments has shown promise in related dental conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * people over 6 years old * people with Primary Failure Eruption Exclusion criteria: * children under 6 years old * endocrine pathology that may interfere with dental eruption * rickets * chemotherapy / radiotherapy * bisphosphonate treatment
Where this trial is running
Strasbourg
- Clinique dentaire — Strasbourg, France (RECRUITING)
Study contacts
- Study coordinator: Marion STRUB, Doctor
- Email: marion.strub@chru-strasbourg.fr
- Phone: 388116956
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Primary Failure of Eruption