Identifying cardiovascular risk in heart failure patients using exercise test data

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to enhance the assessment of cardiovascular risk in patients with heart failure by utilizing the MECKI score, which integrates data from cardiopulmonary exercise testing (CPET) along with cardiac and kidney indexes. The study focuses on patients with left ventricular systolic dysfunction and stable clinical conditions, aiming to identify high-risk individuals through a comprehensive analysis of multiple prognostic factors. By incorporating ventilatory parameters and renal function into existing risk models, the study seeks to provide a more accurate risk estimation for heart failure patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age \>18 past or present heart failure (NYHA functional class I-III, stage C of the ACC/AHA classification)
* documentation of left ventricular systolic dysfunction (LVEF \<40%)
* stable clinical conditions
* previous or concomitant cardiopulmonary exercise test

Exclusion Criteria:

* scheduled cardiovascular treatment
* clinical unstable condition
* History of pulmonary embolism, significant valvular disease, pericardial disease, severe COPD, exercise-induced angina, exercise-induced ECG changes, severe brady- or tachyarrhythmias, or the presence of comorbidities that interfere with exercise performance.

Where it's running

• Centro Cardiologico Monzino
  Milan, Italy, Italy Recruiting
• Ospedali Riuniti di Ancona
  Ancona, Italy Recruiting
• Istituti Clinici Scientifici Maugeri Bari
  Bari, Italy Recruiting
• Ospedale papa Giovanni XXIII
  Bergamo, Italy Recruiting
• Spedali Civili
  Brescia, Italy Recruiting
• Università di Foggia
  Foggia, Italy Recruiting

Study contacts

• Study coordinator: Piergiuseppe Agostoni, Professor
• Email: piergiuseppe.agostoni@ccfm.it
• Phone: +390258002010

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.