Identifying brain lesions in multiple sclerosis using advanced MRI techniques

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of Phase-Sensitive Inversion Recovery (PSIR) MRI in detecting early brain lesions in patients diagnosed with Multiple Sclerosis (MS). It will compare the diagnostic accuracy of PSIR MRI against conventional T2-weighted and Fluid Attenuated Inversion Recovery MRI sequences. Participants aged 15-65 years will be included based on the 2017 McDonald criteria for MS. The study hypothesizes that PSIR MRI will identify more cortical lesions and correlate better with clinical measures than traditional MRI methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 15-65 years.
* Both sexes.
* Patients with MS according to McDonald Criterion

Exclusion Criteria:

* Age less than 15 years old.
* Patients with stroke or previous intracranial hemorrhage.
* Contraindications to MRI scans.
* MS mimics.

Where it's running

• Banha University Hospitals
  Banhā, Qalyubia Governorate, Egypt Recruiting
• El Mounira Multiple Sclerosis Unit
  Cairo, Egypt Recruiting
• Naser Institute MS Unit
  Cairo, Egypt Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.