Identifying biomarkers for early lung cancer detection
NYU Lung Cancer Biomarker Center
This study is trying to find new markers in the body that can help detect lung cancer early in people, especially those who have smoked before.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 3606 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | NYU Langone Health Academic / other |
| Locations | 1 site (New York, New York) |
| Trial ID | NCT00301119 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on identifying and validating biomarkers that can aid in the early detection of lung cancer among individuals at varying risk levels, particularly those with a history of smoking. Participants are divided into two groups: one undergoing screening tests and another for rule-out evaluations of suspicious lung nodules. The study includes comprehensive assessments such as questionnaires, pulmonary function tests, chest CT scans, and potential biopsies to gather tissue samples. The goal is to enhance early diagnosis and treatment planning for lung cancer.
Who should consider this trial
Good fit: Ideal candidates include individuals at high or low risk for lung cancer, particularly those with a significant smoking history or age-related risk factors.
Not a fit: Patients with less than 20 pack years of smoking who are under 50 years of age may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection and treatment strategies for lung cancer, potentially saving lives.
How similar studies have performed: Other studies have shown promise in using biomarkers for cancer detection, indicating that this approach has potential based on previous findings.
Eligibility criteria
Show full inclusion / exclusion criteria
DISEASE CHARACTERISTICS:
* Screening Cohort
* At high- or low-risk for lung cancer
* Smoking history ≥ 20 pack years\*
* With or without workplace exposure to asbestos
* NOTE: \* Participants with \< 20 pack years of smoking are eligible if 50 years of age or older
* Rule-Out Lung cancer group
* Referred for evaluation of suspicious nodules with 1 of the following diagnoses:
* Lung cancer
* Nonmalignant nodules (control group)
PATIENT CHARACTERISTICS:
* Not pregnant
* No prior malignancy except nonmelanoma skin cancer
PRIOR CONCURRENT THERAPY:
* Not specified
Where this trial is running
New York, New York
- NYU Cancer Institute at New York University Medical Center — New York, New York, United States (Recruiting)
Study contacts
- Principal investigator: James J. Tsay, MD, MSc — NYU Langone Health
- Study coordinator: James J. Tsay, MD, MSc
- Email: Jun-Chieh.Tsay@nyulangone.org
- Phone: 212-598-6351
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.