Identifying biomarkers for Alzheimer's disease in the Chinese population

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort study aims to identify biomarkers associated with Alzheimer's disease (AD) in a local Chinese population. Participants will undergo a series of cognitive assessments, blood tests, brain MRI scans, brain PET scans, and retinal imaging at baseline and during six yearly follow-ups. The study hypothesizes that blood-based proteomics, retinal imaging, and advanced imaging techniques can enhance the accuracy of early detection and staging of AD. By focusing on early detection, the study seeks to contribute to the understanding of AD progression and potential interventions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Chinese ethnicity
* \[For dementia group, clinical diagnosis of "probable Alzheimer's disease" according to recommendation from the National Institute on Aging-Alzheimer's Association workgroups (NIA-AA)

Exclusion Criteria:

* Clinical diagnosis of non-AD dementia
* contraindication for MRI or PET

Where it's running

• Chinese University of Hong Kong
  Hong Kong, Hong Hong, Hong Kong Recruiting

Study contacts

• Study coordinator: Pualine Kwan
• Email: paulinekwan@cuhk.edu.hk
• Phone: +852 26352160

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.