Identifying Bertolotti Syndrome using new movement measurements

Precise and Objective Identification of Bertolotti Syndrome Using Novel Kinematic Biomarkers

Observational The Cleveland Clinic · NCT06225583

This study is testing a new way to measure movement and pain in people with Bertolotti Syndrome compared to those with regular lower back pain to see if it helps identify the condition better.

Quick facts

Study typeObservational
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorThe Cleveland Clinic Academic / other
Locations1 site (Cleveland, Ohio)
Trial IDNCT06225583 on ClinicalTrials.gov

What this trial studies

This observational study aims to collect data on lumbar rotations, velocity, and accelerations from patients diagnosed with Bertolotti Syndrome and those with non-Bertolotti lower back pain. Using a novel dynamic visual analog scale (VAS) device, the study will measure pain scores during range-of-motion tasks. The goal is to analyze the differences in kinematics and pain experiences between the two patient groups, which could lead to more precise identification of Bertolotti Syndrome.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older with a confirmed diagnosis of Bertolotti's Syndrome or lower back pain due to sacroiliac pain or lumbosacral facet arthritis.

Not a fit: Patients with a history of spinal deformity, previous spinal surgeries, spinal infections, or who are pregnant may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve the accuracy of diagnosing Bertolotti Syndrome, leading to better-targeted treatments for patients.

How similar studies have performed: While this approach is innovative, it builds on existing methodologies for assessing movement and pain, but specific prior successes in this exact context are not documented.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Lower Back Pain Cohort

* Positive diagnosis of sacroiliac pain or lumbosacral facet arthritis pain
* Age ≥ 18 years

Bertolotti's Syndrome Cohort

* Positive diagnosis of Bertolotti's Syndrome
* Age ≥ 18 years
* Positive imaging for Bertolotti's Syndrome
* Previous analgesic injection results

Exclusion Criteria:

Lower Back Pain Cohort

* History of spinal deformity, previous spinal surgeries, spinal infections
* Pregnant women

Bertolotti's Syndrome Cohort

* History of spinal deformity, previous spinal surgeries, spinal infections
* Pregnant women

Where this trial is running

Cleveland, Ohio

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Bertolotti's SyndromeLower Back Pain
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.