Identifying autoantibodies before immune therapy for cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to identify biomarkers that predict the development of autoimmune side effects in patients undergoing immune checkpoint inhibitor therapy for cancer. By analyzing blood samples for specific autoantibodies, the researchers hope to determine if the presence of these antibodies can indicate both the likelihood of adverse effects and the potential for improved cancer outcomes. The focus is particularly on thyroid autoantibodies and their correlation with thyroiditis and oncologic prognosis, as well as exploring less common endocrinopathies. The study will include all eligible patients consenting to participate at the specified locations in Brussels.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All subjects eligible for immune checkpoint therapy at the participating study sites. The cohort will consist of all subjects who consent to participate, and to use their information for future research and publication in a scientific journal.

Exclusion Criteria:

* Pregnancy

Where it's running

• C.H.U. Saint-Pierre
  Brussels, Belgium Recruiting
• CHU Brugmann
  Brussels, Belgium Recruiting
• HUB - Institut Jules Bordet
  Brussels, Belgium Recruiting

Study contacts

• Study coordinator: Jeroen de Filette, MD
• Email: Jeroen.DEFILETTE@chu-brugmann.be
• Phone: 024772067

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.