Identifying and differentiating thyroid nodules using acoustic imaging

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify and differentiate thyroid nodules through advanced acoustic imaging techniques and viscoelastic parameters. It will evaluate the effectiveness of vibro-acoustography in detecting thyroid nodules and compare its specificity in distinguishing between malignant and benign nodules against traditional ultrasound methods. Additionally, the study will assess the diagnostic value of Shear Wave Ultrasound Vibrometry and Comb Push shear elastography in correlating results with pathology. The study will also explore the response to alcohol ablation in patients with recurrent thyroid cancer.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* \* Male and female patient volunteers ages 8 and up who are suspicious for thyroid cancer

  * Patients who have palpable and sonographically detectable lymph nodes or nonthyroidal neck masses and are referred to Radiology Department or Endocrinology for fine-needle aspiration biopsy (FNAB)
  * Patients 18 and up who were previously diagnosed with thyroid cancer and treated with thyroidectomy and recently diagnosed as having recurrence nodes on thyroid bed or on their neck

Exclusion Criteria:

* Because thyroid cancer is rare under the age of 8 years, children younger than this age are excluded from the study
* Having FNAB or surgical biopsy on thyroid in less than two weeks for thyroid nodule detection group
* Having FNAB or surgical biopsy on cervical lymph nodes or non- thyroidal masses for this group of patients

Where it's running

• Mayo Clinic in Arizona
  Scottsdale, Arizona, United States Recruiting
• Mayo Clinic in Florida
  Jacksonville, Florida, United States Recruiting
• Mayo Clinic in Rochester
  Rochester, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Azra Alizad, MD — Mayo Clinic in Rochester
• Study coordinator: Clinical Trials Referral Office
• Email: mayocliniccancerstudies@mayo.edu
• Phone: 855-776-0015

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Evaluating DNA Methylation for Diagnosing Thyroid Nodules

  This study is testing a new DNA test to see if it can help doctors tell the difference between cancerous and non-cancerous thyroid nodules to reduce unnecessary surgeries.

  Recruiting City of Hope Medical Center · Duarte, California · NCT05229341

• Developing blood tests for diagnosing thyroid cancer

  This study is testing a new blood test to help doctors tell if thyroid nodules are cancerous or not, using samples from patients with suspicious nodules or thyroid cancer.

  Recruiting Jonsson Comprehensive Cancer Center · Los Angeles, California · NCT04742608

• Investigational imaging for monitoring treatment response in thyroid cancer and head and neck malignancies

  This study is testing if a special type of MRI can help doctors see how well treatment is working for people with thyroid cancer and head and neck cancers.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT04589624

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.