Hysteroscopic removal versus manual vacuum aspiration for early miscarriage

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares hysteroscopic resection to ultrasound-guided manual vacuum aspiration for management of early (under 9 weeks) nonviable singleton pregnancies. Eligible adult women (18–55) who choose surgical management will undergo one of the two surgical approaches and be followed for resolution of retained products, return of beta-hCG to negative, need for repeat procedures, and development of intrauterine adhesions. Procedures are performed by gynecologic surgeons at University Hospitals with standard perioperative care and ultrasound guidance for the MVA arm. Outcomes and complications will be recorded to determine whether hysteroscopic resection offers faster or more complete removal of tissue than manual vacuum aspiration.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult women age 18-55
* Ultrasound Diagnosis of Early Pregnancy Loss
* \< 9 weeks gestational age as determined by ultrasound
* Singleton non-viable pregnancy
* Stated and willingness to comply with all study procedures and availability for the duration of the study
* Provision of signed and dated informed consent form
* Chose a surgical method of management for fetal loss

Exclusion Criteria:

* Pregnancy of Unknown Location
* Current, viable pregnancy
* Prior medical treatment for this early pregnancy loss
* Contraindications to surgical management
* Active infection (i.e. fever, chills, fundal tenderness)
* Pre-existing coagulopathies

Where it's running

• University Hospitals
  Cleveland, Ohio, United States Recruiting

Study contacts

• Principal investigator: Joseph Findley, MD — University Hospitals
• Study coordinator: Kylie Phillips
• Email: kylie.phillips@uhhospitals.org
• Phone: 216-285-5028

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.