Hypnosis to improve well-being after an ICU stay
Hypnosis to Improve Well-beings of Critically Ill Patients and Prevent Post-intensive Care Syndrome
This trial will test whether short hypnosis sessions given at ICU discharge and again 7 and 14 days later help ICU survivors feel better by day 28.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Geneva Academic / other |
| Locations | 2 sites (Geneva and 1 other locations) |
| Trial ID | NCT07254299 on ClinicalTrials.gov |
What this trial studies
Critically ill adults who were mechanically ventilated for at least two days and can give consent are randomly assigned to receive either standard post-ICU care or standard care plus three brief hypnosis sessions (at ICU discharge, day 7, and day 14 if still hospitalized). The main outcome is patient-reported well-being measured at 28 days after ICU discharge. Patients with delirium, reduced consciousness, traumatic brain injury, planned withdrawal of care, or non-French speakers are excluded. The trial is conducted at tertiary hospitals in Geneva and Neuchâtel using standardized hypnosis protocols delivered by trained staff.
Who should consider this trial
Good fit: Ideal candidates are French-speaking adult ICU survivors who were mechanically ventilated for at least two days, are lucid (GCS 15), not delirious at discharge, and able to provide informed consent.
Not a fit: Patients who are non-French-speaking, have ongoing delirium or lowered consciousness, traumatic brain injury, planned withdrawal of care, or very prolonged ICU stays are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, hypnosis could offer a low-risk, non-drug way to improve short-term well-being after ICU and potentially reduce components of post-intensive care syndrome.
How similar studies have performed: Small studies in burn care and non-invasive ventilation have shown hypnosis can reduce pain and anxiety and improve comfort, but using hypnosis specifically to prevent post-intensive care syndrome is relatively novel and less well tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * On Mechanical Ventilation for at least 2 days * Able to give informed consent as documented by signature * French speaking Exclusion Criteria: * Refusal of the patient * Patient transferred from another ICU * Patient is planned for a withdrawal of care or is actively dying * Glasgow coma scale (GCS) \<15 on ICU discharge * Patient presenting with delirium (detected by CAM-ICU) on ICU discharge * Patient hospitalized for traumatic brain injury * Patient is in jail * Patient hospitalized for more than 28 days in the ICU
Where this trial is running
Geneva and 1 other locations
- University Hospital of Geneva — Geneva, Switzerland (Recruiting)
- Hôpitaux Neuchâtelois — Neuchâtel, Switzerland (Not_yet_recruiting)
Study contacts
- Principal investigator: Hannah Wozniak, Medical Doctor — University Hospital, Geneva
- Study coordinator: Hannah Wozniak, Medical Doctor
- Email: hannah-wozniak@hug.ch
- Phone: +41
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.