Hyperbaric oxygen effects on circulating blood-forming stem cells

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional protocol enrolls adults aged 20–80 who are intending to start hyperbaric oxygen therapy for a separate indication and agree to give blood samples. Participants will have serial blood draws before, during, and after a course of HBOT to measure circulating hematopoietic stem and progenitor cell populations using flow cytometry and related laboratory tests. People with active or recent infection, active malignancy, known hematopoietic disease, low B12 or iron, or abnormal leukocyte counts are excluded. The project aims to document whether HBOT sessions produce measurable increases in circulating HSCs and to characterize the timing of any changes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The study will include patients aged 20-80 who are intendent to start HBOT for other indication that are willing to give blood samples for measurements of circulating stem cells.

Exclusion Criteria:

1. Active or recent infection within the last month
2. Active malignancy.
3. History of hematopoietic disease
4. Low B12 or iron levels
5. Inability to sign the informed consent form
6. Leucocytes ˂4000 or ˃10,000

Where it's running

• The Sagol Center for Hyperbaric Medicine and Research Shamir Medical Center (Assaf Harofeh)
  Zrifin, Israel Recruiting

Study contacts

• Study coordinator: Shai Efrati, Prof
• Email: efratishai@outlook.com
• Phone: 972549212866

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.