Hydrolyzed versus standard whey protein for cholesterol control
Hydrolyzed Whey for Blood Lipid Control
This trial will test whether a daily hydrolyzed whey protein drink helps adults with high‑end normal to mildly elevated cholesterol keep their cholesterol in the normal range.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 72 (estimated) |
| Ages | 21 Years to 59 Years |
| Sex | All |
| Sponsor | Medinutra LLC Academic / other |
| Locations | 1 site (Dublin, Ohio) |
| Trial ID | NCT07101263 on ClinicalTrials.gov |
What this trial studies
Adults aged 21–59 with total cholesterol between 190 and 225 mg/dL are enrolled and given either a hydrolyzed whey beverage or a conventional whey control once daily for six weeks. Blood is drawn at a LabCorp location before and after the intervention to measure serum cholesterol and a general inflammation marker plus two related blood measures. People on statins, with active liver disease, uncontrolled diabetes, certain inflammatory or hormonal disorders, smokers, heavy drinkers, pregnant or breastfeeding people, and those with milk protein allergies are excluded. The study is sponsored by Medinutra LLC and conducted at a single site in Dublin, Ohio.
Who should consider this trial
Good fit: Adults 21–59 years old with total cholesterol of 190–225 mg/dL who are not taking statins and who meet the study's health and lifestyle criteria.
Not a fit: People with active liver disease, uncontrolled diabetes, inflammatory disorders, current smokers, those on statins, pregnant or breastfeeding individuals, or anyone allergic to milk protein are excluded and unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, the hydrolyzed whey could provide a modest, non‑drug option to help people keep cholesterol in the normal range.
How similar studies have performed: Existing evidence is limited and mixed—small unpublished reports and one retracted larger report have suggested cholesterol reductions with hydrolyzed whey, but results are inconsistent and not well validated.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Cholesterol reading of 190 to 225 mg/dL * Age 21-59 years old Exclusion Criteria: * Uncontrolled diabetes * Hypothyroidism or other hormonal problems that have not stabilized * Any liver diseases being actively treated * Cancer * Renal dialysis use * Rheumatoid arthritis and related issues like lupus * Inflammatory bowel disease * Smoking * Following a very restrictive diet * Low blood pressure * Statin drug use * Having more than 5 alcoholic drinks per week * Extreme obesity (BMI over 37) * Pregnancy or lactation * Allergies to milk protein * History of discomfort after consuming whey protein
Where this trial is running
Dublin, Ohio
- Medinutra LLC — Dublin, Ohio, United States (Recruiting)
Study contacts
- Study coordinator: Robert DiSilvestro, Ph.D.
- Email: nutritionstudy111@gmail.com
- Phone: 614=348-9375
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.