Hydrogen water for treating chronic fatigue syndrome
Hydrogen Water Dosing Study for ME/CFS and Chronic Fatigue
This study is testing if drinking hydrogen water can help people with chronic fatigue syndrome feel less tired and improve their overall well-being.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Stony Brook University Academic / other |
| Locations | 1 site (Stony Brook, New York) |
| Trial ID | NCT06227273 on ClinicalTrials.gov |
What this trial studies
This 16-week pilot trial aims to evaluate the effects of hydrogen water on symptoms of chronic fatigue syndrome (CFS). Participants will be randomized into two groups: one receiving a consistent low dose of hydrogen water, and the other starting with a low dose followed by a higher dose after eight weeks. The study will assess fatigue, physical function, and stress through online evaluations, as well as measure oxidative stress using a salivary biomarker. The goal is to determine if a higher dosage after acclimatization leads to better outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 who meet the criteria for myalgic encephalomyelitis/chronic fatigue syndrome and are physically capable of participating.
Not a fit: Patients with fatigue due to other medical conditions or significant psychiatric disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a novel and safe treatment option for patients suffering from chronic fatigue syndrome.
How similar studies have performed: Previous studies have shown mixed results with hydrogen water, indicating potential but not definitive efficacy, making this approach somewhat novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: - Patients aged 18-65 of both sexes; considered physically capable and willing to perform the study tasks. * Meeting validated phone-screen eligibility for ME/CFS criteria. * Patient has internet and computer. Exclusion Criteria: Cases of fatigue clearly attributable to self-report medical conditions such as untreated hypothyroidism, unstable diabetes mellitus, organ failure, chronic infections, and chronic inflammatory diseases, or AIDS. __ Exclusionary psychiatric disorders include any psychosis, or alcohol/ substance abuse within two years prior to illness onset and any time afterward, and current or past depression with melancholic or psychotic features within 5 years prior to onset of ME/CFS or anytime afterward * Pregnancy is an exclusion. * Patients with BMI\>35. * Patients at significant risk of suicide or in need of urgent psychiatric treatment. As much as possible, appropriate medical and psychiatric referrals to facilities local to subjects will be provided.
Where this trial is running
Stony Brook, New York
- Fred Friedberg — Stony Brook, New York, United States (Recruiting)
Study contacts
- Study coordinator: Fred Friedberg, PhD
- Email: fred.friedberg@stonybrookmedicine.edu
- Phone: 631-638-1931
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.