Hybrid robot-assisted training for upper limb recovery after stroke

The Study Firstly Proposes a Hybrid Robot-assisted Training Program, Which Combines Two Types of Robotic Systems, to Enhance the Effectiveness of Robot-assisted Training and Provide a New Approach for Motor Training of Upper Limb in Stroke Patients

Not applicable Interventional Chang Gung Memorial Hospital · NCT05226988

This study is testing whether a new type of robot-assisted training can help stroke survivors improve their arm movement and everyday activities better than traditional rehab methods.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment70 (estimated)
Ages25 Years to 75 Years
SexAll
SponsorChang Gung Memorial Hospital Academic / other
Locations1 site (Taoyuan)
Trial IDNCT05226988 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of hybrid robot-assisted training, which combines exoskeleton and end-effector devices, on stroke patients' motor performance and daily functioning. Participants will be randomly assigned to receive either hybrid training, exoskeleton training, end-effector training, or conventional rehabilitation over six weeks, with three sessions per week. The study aims to assess both immediate and long-term outcomes, including quality of life and self-efficacy, in individuals with chronic upper limb dysfunction following a stroke.

Who should consider this trial

Good fit: Ideal candidates are stroke survivors with unilateral paresis who have had their stroke for more than three months and can provide informed consent.

Not a fit: Patients with other neurological diseases or severe cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve motor function and quality of life for stroke survivors.

How similar studies have performed: Previous studies have shown mixed results regarding the effectiveness of robot-assisted training, making this hybrid approach a novel exploration in the field.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Stroke more than 3 months.
* Modified Ashworth Scale proximal part ≤ 3, Modified Ashworth Scale distal part ≤ 2, and no serious muscle spasms.
* The myoelectric signal can be detected to activate the instrument
* Unilateral paresis (FMA score\<60)
* No serious cognitive impairment (i.e., Mini Mental State Exam score \> 24)
* Can provide informed consent

Exclusion Criteria:

* Other neurological disease
* Complete sense of body defect
* Inability to understand instructions
* current participation in any other research
* Botulinum Toxin injection within 3 months

Where this trial is running

Taoyuan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Strokeneurorehabilitationrobot-assisted trainingupper extremitymotor control
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.