Hybrid mirror-primed rehabilitation for unilateral stroke
Official title: Hybrid Stroke Rehabilitation With Mirror Priming
Run by I-Shou University · NCT07324278 · Data updated 2026-11-12
This trial will test whether adding enhanced mirror priming to conventional therapy helps adults who had a first-time one-sided stroke at least three months ago improve upper-arm movement.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 80 Years |
| Sex | All |
| Enrollment | 81 (estimated) |
| Sponsor | I-Shou University Academic / other |
| Locations | 1 site (Kaohsiung City, Yanchao District) |
| Status | Recruiting |
| Started | February 2, 2026 |
| Main results expected | September 30, 2030 |
| Study ends | December 31, 2030 |
| Registry record updated | August 25, 2026 |
| Trial ID | NCT07324278 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 20–80 with a first-ever unilateral stroke at least three months earlier, a baseline FMA-UE score greater than 10, no severe spasticity in the affected arm, and the ability to follow instructions and provide consent.
✕Probably not a fit
Patients with severe spasticity, very low baseline motor scores, unstable medical conditions, or those within three months of a stroke are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares an enhanced mirror priming approach combined with conventional therapy to conventional therapy alone to optimize and personalize upper-limb rehabilitation after unilateral stroke. Participants are adults aged 20–80 with a first-ever unilateral stroke at least three months prior and a baseline Fugl-Meyer Assessment Upper Extremity score above 10, with no severe spasticity and the ability to follow instructions. The program delivers supervised in-person sessions at E-Da Hospital where mirror-priming procedures are applied alongside standard rehabilitation exercises to promote motor relearning. Primary outcomes will focus on changes in upper-extremity motor function and the tolerability of the enhanced priming protocol.
Why it matters
Potential benefit: If successful, the approach could improve upper-arm motor recovery and enable more personalized rehabilitation plans for people with chronic unilateral stroke.
How similar studies have gone: Traditional mirror therapy has shown modest motor benefits in prior studies, while enhanced or hybrid mirror-priming approaches are relatively novel with limited published evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. A first-ever unilateral stroke ≥3 months 2. Age between 20 and 80 years 3. Baseline Fugl-Meyer Assessment Upper Extremity (FMA-UE) score ≥ 10 4. No severe spasticity in any joints of the affected arm 5. Ability to follow the instructions 6. No participation in other studies during the study period 7. Willingness to provide informed written consent. Exclusion Criteria: 1. Serious medical problems or poor physical conditions that might be detrimental to study participation. 2. Received or planned botulinum toxin injections within 3 months prior to or during the trial
Where it's running
-
E-Da Hospital
Kaohsiung City, Yanchao District, Taiwan Recruiting
Study contacts
- Study coordinator: Yi-chun Li, PhD
- Email: joyjoyfish@gmail.com
- Phone: +886-7-6151100
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.