Hyaluronic acid fillers for lips, cheeks, nasolabial folds, perioral lines, and under-eye hollows in everyday practice

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This post-market interventional protocol delivers hyaluronic acid-based dermal filler injections to adults seeking aesthetic correction of specified facial areas and follows outcomes under routine clinical conditions. Participants receive an initial injection and attend follow-up visits every six months up to 24 months, with optional retreatment at 12 or 18 months if desired. At each visit the investigator performs a brief clinical exam and participants rate their aesthetic improvement compared with pre-injection appearance and report pain from the initial injection. The primary focus is on duration of effect and ongoing monitoring for device-related adverse events in real-life use.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subject seeking an aesthetic correction of the infraorbital hollows with FASY P and/ or an aesthetic correction of the lips with ESTYME® LIPS, and/ or an aesthetic correction of the perioral lines with ESTYME® SMOOTH, and/ or an aesthetic correction of nasolabial folds with ESTYME® SMOOTH, and/ or an aesthetic correction of cheeks with ESTYME® SCULPT.
* Subject who agreed to participate and have signed an informed consent.
* Age: over 18 years old.
* Subject being affiliated to a health social security system.

Exclusion Criteria:

* Minors
* Subjects with a known allergy to hyaluronic acid, lidocaine or amide local anesthetics.
* Subjects with porphyria.
* Subjects with an autoimmune disorder, or using an immunosuppressant medication.
* Pregnant or breastfeeding women.
* Subjects with inflammation, infection or cutaneous disorders, at the treatment site or nearby.
* Subjects with bleeding disorders or in subjects receiving thrombolytic or anticoagulant treatment.
* Areas other than those recommended by the IFU.
* Subject deprived of liberty by judicial or administrative decision.
* Adults under a legal protection measure (guardianship/curatorship).
* Subject under legal protection order.

Where it's running

• Centre Médical Saint Jean
  Arras, France Recruiting
• Cabinet médical
  Lyon, France Recruiting
• Palais de Flore
  Lyon, France Recruiting
• Centre Laser Palaiseau
  Palaiseau, France Recruiting
• Aesthé - Marais.
  Paris, France Recruiting
• Cabinet médical
  Paris, France Recruiting

Study contacts

• Study coordinator: Valentin BONVALET
• Email: v.bonvalet@symatese.com
• Phone: +33 (0)4 78 56 72 80

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Injectable hyaluronic acid filler for lips, nasolabial folds, and midface volume

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• DMFI300 versus Ellansé‑M for nasolabial fold wrinkles

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.