HPV screening for women aged 23-29
Official title: Evaluation of Organized Human Papilloma Virus (HPV) Screening of 23-29-year-old Women
Run by Karolinska Institutet · NCT05229679 · Data updated 2026-11-12
This study tests if using HPV screening can better protect women aged 23-29 from cervical cancer compared to the usual method of checking cells.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 23 Years to 29 Years |
| Sex | Women only |
| Enrollment | 180000 (estimated) |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 2 sites (Lund, Skåne County and 1 other locations) |
| Status | Recruiting |
| Started | November 16, 2020 |
| Main results expected | December 31, 2038 |
| Study ends | December 31, 2038 |
| Registry record updated | March 19, 2025 |
| Trial ID | NCT05229679 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women aged 23-29 who are invited for cervical cancer screening.
✕Probably not a fit
Women who do not attend the screening or do not provide consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This trial investigates whether organized screening using primary HPV analysis offers better cancer protection for women aged 23-29 compared to the traditional method of cytology. The study will involve women born between 1991 and 1997 in the Stockholm and Skåne regions of Sweden. Participants will undergo cell sampling and analysis to determine the effectiveness of HPV testing in preventing cervical cancer and related conditions.
Why it matters
Potential benefit: If successful, this approach could significantly enhance cervical cancer prevention for young women.
How similar studies have gone: Previous studies have shown promising results with HPV-based screening approaches, indicating potential for success in this trial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women ages 23-29 invited to screening. Exclusion Criteria: * Women who do not show up for screening or do not consent.
Where it's running
-
Region Stockholm
Stockholm, Sweden Recruiting -
Region of Skåne
Lund, Skåne County, Sweden Active not recruiting
Study contacts
- Principal investigator: Joakim Dillner, MD, PhD — Karolinska University Hospital/Karolinska Institutet
- Study coordinator: Joakim Dillner, MD, PhD
- Email: joakim.dillner@ki.se
- Phone: +46 (0) 72-468 24 60
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
CHW4CervixHealth: HPV self-collection kits with community health workers
This project will test whether giving self-collection HPV kits during community workshops led by community health workers helps increase screening among under-screened women aged 25–65 and will first compare kit results to clinical Pap smears.
-
HPV self-sampling to improve cervical screening for women in Zaporizhzhia during the war
This project will test whether giving women aged 30–60 in Zaporizhzhia HPV self-sampling kits can keep cervical screening going when clinic access is disrupted by the war.
-
Investigating HPV and skin cancer risks in organ transplant recipients
This study is trying to see if organ transplant recipients have a higher risk of HPV infections and skin cancer compared to people with normal immune systems.
-
Cervical screening and care options for women living with HIV who test positive for high-risk HPV
This study tests different ways to screen and manage high-risk HPV in women with HIV to see what might work best for them.
-
Hydrogel spacer to protect the rectum during cervical cancer radiotherapy
This study tests whether placing an absorbable hydrogel spacer between the cervix/vagina and rectum before definitive radiotherapy can reduce rectal radiation exposure for women with cervical cancer.
-
How cinema sessions during chemotherapy might help cervical cancer patients
We’re testing if watching films during chemotherapy helps cervical cancer patients feel less anxious and improve quality of life.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.