Clinical trial Recruiting at 1 site Interventional Ages 23 to 29 Women only

HPV screening for women aged 23-29

Official title: Evaluation of Organized Human Papilloma Virus (HPV) Screening of 23-29-year-old Women

Run by Karolinska Institutet · NCT05229679 · Data updated 2026-11-12

This study tests if using HPV screening can better protect women aged 23-29 from cervical cancer compared to the usual method of checking cells.

Quick facts

Study typeInterventional
Ages23 Years to 29 Years
SexWomen only
Enrollment180000 (estimated)
SponsorKarolinska Institutet
Academic / other
Locations2 sites (Lund, Skåne County and 1 other locations)
StatusRecruiting
StartedNovember 16, 2020
Main results expectedDecember 31, 2038
Study endsDecember 31, 2038
Registry record updatedMarch 19, 2025
Trial IDNCT05229679 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are women aged 23-29 who are invited for cervical cancer screening.

Probably not a fit

Women who do not attend the screening or do not provide consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates whether organized screening using primary HPV analysis offers better cancer protection for women aged 23-29 compared to the traditional method of cytology. The study will involve women born between 1991 and 1997 in the Stockholm and Skåne regions of Sweden. Participants will undergo cell sampling and analysis to determine the effectiveness of HPV testing in preventing cervical cancer and related conditions.

Why it matters

Potential benefit: If successful, this approach could significantly enhance cervical cancer prevention for young women.

How similar studies have gone: Previous studies have shown promising results with HPV-based screening approaches, indicating potential for success in this trial.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Women ages 23-29 invited to screening.

Exclusion Criteria:

* Women who do not show up for screening or do not consent.

Where it's running

  • Region Stockholm
    Stockholm, Sweden
    Recruiting
  • Region of Skåne
    Lund, Skåne County, Sweden
    Active not recruiting

Study contacts

  • Principal investigator: Joakim Dillner, MD, PhD — Karolinska University Hospital/Karolinska Institutet
  • Study coordinator: Joakim Dillner, MD, PhD
  • Email: joakim.dillner@ki.se
  • Phone: +46 (0) 72-468 24 60

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.