How two shoulder nerve block techniques affect brain and carotid oxygen levels
Official title: Comparison Of The Effect Of Interscalene Block Alone And The Combination Of Interscalene Block And Superficial Cervical Block On Brain Oxygenation And Carotid Artery Diameter In Shoulder Surgery
Run by Sanliurfa Mehmet Akif Inan Education and Research Hospital · NCT07398352 · Data updated 2026-11-12
We are testing whether adding a superficial cervical plexus block to a standard interscalene nerve block changes brain oxygen levels, carotid artery size, intraoperative stability, and pain for adults having shoulder surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | Sanliurfa Mehmet Akif Inan Education and Research Hospital Academic / other |
| Locations | 1 site (Sanliurfa) |
| Status | Recruiting |
| Started | February 23, 2026 |
| Main results expected | December 15, 2026 |
| Study ends | December 15, 2026 |
| Registry record updated | March 24, 2026 |
| Trial ID | NCT07398352 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–65 years old with ASA physical status I–II who are scheduled for shoulder surgery and have no contraindications to regional anesthesia are ideal candidates.
✕Probably not a fit
Patients with prior stroke, carotid endarterectomy, severe organ failure, BMI over 35, ASA III–V status, pregnancy, breastfeeding, or other contraindications to regional anesthesia are excluded and unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults scheduled for shoulder surgery will receive either an interscalene brachial plexus block alone or an interscalene block combined with a superficial cervical plexus block. Cerebral oxygenation will be monitored noninvasively with near-infrared spectroscopy (NIRS) and carotid artery diameter measured with ultrasound before and during surgery. Intraoperative hemodynamics, laboratory parameters, clinical course, and postoperative pain will also be recorded. The protocol compares these physiologic and clinical outcomes between the two block techniques to determine differences in safety and analgesia.
Why it matters
Potential benefit: If successful, adding the superficial cervical plexus block could improve pain control without reducing cerebral oxygenation or impairing carotid blood flow.
How similar studies have gone: Interscalene block is well established for shoulder analgesia and combinations with superficial cervical blocks have shown improved pain control in other reports, but effects specifically on cerebral oxygenation and carotid diameter are less well studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-65 years patient * American Society of Anesthesiologists (ASA) I-II patient Exclusion Criteria: * Age \< 18 years or \> 65 years * History of carotid endarterectomy * History of cerebrovascular accident(CVA) * Body Mass index (BMI)\>35 kg/m² * Inability to cooperate or comply with study procedures * Liver and kidney failure * Pregnancy and breastfeeding * ASA pyhsical status III-V * Contraindication to regional anesthesia
Where it's running
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Sanliurfa Mehmet Akif Inan Education and Research Hospital
Sanliurfa, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Ramazan ASLANPARÇASI, MD — Sanliurfa Mehmet Akif Inan Education and Research Hospital
- Study coordinator: Ramazan ASLANPARÇASI, MD
- Email: rmzn.aslan.2015@gmail.com
- Phone: +905532980247
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.