How tongue, lip, and cheek pressures relate to upper jaw narrowness.
Investigation of the Effect of Lip, Cheek, and Tongue Muscle Pressure on Maxillary Transverse Development
This test will see if tongue, lip, and cheek pressures are linked to narrow upper jaws in people aged 12 to 25.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 12 Years to 25 Years |
| Sex | All |
| Sponsor | Yuzuncu Yil University Academic / other |
| Locations | 1 site (Van, Van) |
| Trial ID | NCT07552441 on ClinicalTrials.gov |
What this trial studies
This randomized clinical study measures tongue, lip, and cheek pressures with orolingual manometry (IOPI Pro Deluxe) and compares participants who have maxillary transverse constriction to controls with normal transverse width. Eligible participants are 12–25 years old, have permanent dentition and skeletal Class I alignment, and are grouped by clinical and radiographic diagnosis of constriction versus normal width. Key exclusions include prior orthodontic or orthognathic surgery, craniofacial syndromes, neuromuscular disorders, significant facial trauma, macroglossia or severe ankyloglossia, and medications that affect muscle tone. The goal is to identify pressure patterns that may contribute to upper jaw narrowness and inform more stable orthodontic or myofunctional approaches.
Who should consider this trial
Good fit: Ideal candidates are people aged 12–25 with permanent dentition and skeletal Class I alignment who either have clinically and radiographically confirmed maxillary transversal constriction or normal maxillary width and can follow IOPI testing instructions.
Not a fit: Patients who have had prior orthodontic or jaw surgery, craniofacial syndromes, neuromuscular disease, macroglossia or severe tongue-tie, or who take medications that affect muscle tone are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the findings could help clinicians customize orthodontic and myofunctional treatments to improve jaw width and long-term stability.
How similar studies have performed: Prior work has used devices like the IOPI to measure tongue strength and shown links between orofacial muscle function and dental arch form, but randomized evidence directly connecting muscle pressures to maxillary development remains limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:Participants aged between 12 and 25 years.Diagnosed as Skeletal Class I (ANB angle: $0\^\\circ$ to $4\^\\circ$).Experimental Group: Clinical and radiographic diagnosis of maxillary transversal constriction.Control Group: Normal maxillary transversal width with no crossbite or constriction.Permanent dentition (excluding third molars).Good oral hygiene and no active periodontal disease.Ability to understand and follow instructions for the IOPI measurement protocol. \- Exclusion Criteria:Previous orthodontic or orthognathic surgical treatment. History of craniofacial anomalies or syndromes (e.g., cleft lip and palate). Neuromuscular disorders or systemic diseases affecting muscle function. History of trauma to the jaw or facial region. Congenitally missing teeth (hypodontia) or extensive prosthetic restorations. Macroglossia or severe tongue-tie (ankyloglossia). Use of medications that may influence muscle tone (e.g., muscle relaxants). Presence of large tonsils or adenoids that significantly obstruct the airway. \-
Where this trial is running
Van, Van
- Van Yüzüncü Yıl University, Faculty of Dentistry, Department of Orthodontics — Van, Van, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Saadet Çınarsoy Ciğerim, assoc prof
- Email: saadetcinarsoy@live.com
- Phone: +905054870692
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.