How the implant-to-bone gap affects labial bone thickness after replacing a broken upper front tooth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Patients with a bounded non-restorable upper anterior tooth will receive immediate implant placement using a surgical guide and will be assigned to one of two groups based on the horizontal defect distance (jumping gap) either <2 mm or ≥2 mm. Labial bone thickness will be measured preoperatively on CBCT and confirmed at surgery, and patients will return for clinical checks and radiographs every three months up to one year. The study compares changes in labial bone thickness, soft-tissue quality, esthetic outcomes, and patient-reported satisfaction between the two gap groups. The trial is conducted at the Department of Periodontology, Faculty of Dentistry, Cairo University, with participants recruited from its outpatient clinic.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with a bounded single non-restorable upper tooth in the anterior maxilla (15-25) FDI (El Ebiary et al., 2023b)
2. Patients with an age range of 21 to 65 years old (Levine et al., 2022)
3. Patients with good oral hygiene with BoP ≤ 10 % (Chapple et al., 2018)
4. Compliant patients willing to follow up to one year.
5. Remaining labial bone thickness ≥ 1mm measured on C.B.C.T. and confirmed on the day of surgery after tooth extraction and before final implant placement.

Exclusion Criteria:

1. The presence of acute/active infection related to the non-restorable tooth (Block et al., 2009) cited in (Soegiantho et al., 2023)
2. Presence of labial bone defect as fenestration/dehiscence (Crespi et al., 2008) cited in (Soegiantho et al., 2023)
3. Large cyst or pathological lesion related to the tooth (Tallarico et al., 2016-2017) cited in (Soegiantho et al., 2023); (Morton, Wismeijer, Chen, Hamilton, Wittneben, Casentini, Gonzaga, Lazarin, Martin, Molinero-Mourelle, et al., 2023)
4. History of radiation to the maxilla (Cannizzaro et al., 2010) cited in (Soegiantho et al., 2023)
5. History of bisphosphonate therapy or other anti-resorptive agents (Cannizzaro et al., 2010) cited in (Soegiantho et al., 2023)
6. Uncontrolled systemic or metabolic disease. (Cecchinato et al., 2015) cited in (Soegiantho et al., 2023)
7. Patients with parafunctional habits or active periodontitis (Cannizzaro et al., 2010) cited in (Soegiantho et al., 2023) 8- Tobacco abuse (\>10 cigarettes per day) (Canullo et al., 2010) cited in (Soegiantho et al., 2023)

9- Alcohol abuse (Block et al., 2009) cited in (Soegiantho et al., 2023)

Where it's running

• Cairo University
  Cairo, Egypt Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.