Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

How social support changes threat-related vigilance and arousal

Official title: Effects of Trauma and Discrimination on the Social Regulation of Threat-related Vigilance and Arousal

Run by University of Nevada, Reno · NCT05558527 · Data updated 2026-11-12

This study will test whether having a supportive romantic partner present reduces threat-related vigilance and physiological arousal in adults in stable relationships, and whether histories of interpersonal trauma or racial/ethnic discrimination change that effect.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment45 (estimated)
SponsorUniversity of Nevada, Reno
Academic / other
Locations1 site (Reno, Nevada)
StatusRecruiting
StartedDecember 18, 2025
Main results expectedDecember 2028
Study endsDecember 2029
Registry record updatedApril 13, 2026
Trial IDNCT05558527 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal participants are adults in a stable romantic relationship for at least six months, fluent in English, with normal or allowable corrected vision (not requiring glasses or hard/bifocal contacts), and who have not experienced a traumatic event in the past four weeks.

Probably not a fit

People who are not in a qualifying romantic relationship, require glasses or disallowed contact lenses, have very recent trauma, or cannot travel to Reno are unlikely to be eligible or to benefit from participating.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will use eye-tracking and physiological measures to compare vigilance and arousal when participants view potential threat cues with a romantic partner present versus alone. Participants must be adults in stable romantic relationships, fluent in English, and have normal or allowable corrected vision. The team will gather self-reported histories of interpersonal trauma and ethnoracial discrimination to see if those histories moderate the social buffering effect. All procedures take place in controlled laboratory visits at the University of Nevada, Reno contrasting social support and no-support conditions.

Why it matters

Potential benefit: If successful, the findings could support partner-based strategies to reduce hypervigilance and excessive arousal in people with trauma or discrimination histories.

How similar studies have gone: Prior research supports social emotion regulation as a buffer for arousal, but using eye-tracking to study hypervigilance and testing moderation by interpersonal trauma and ethnoracial discrimination is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* In a stable romantic relationship for 6 months or more
* Normal vision or corrected-to-normal vision
* Fluent in English

Exclusion Criteria:

* If vision is corrected-to-normal, needs to use hard contact lenses, bifocal contact lenses, or glasses
* Experienced a traumatic event within the past 4 weeks

Where it's running

  • University of Nevada, Reno
    Reno, Nevada, United States
    Recruiting

Study contacts

  • Principal investigator: Cynthia L Lancaster, PhD — University of Nevada, Reno
  • Study coordinator: Kylie Baer, MS
  • Email: kyliebaer@unr.edu
  • Phone: (775) 682-8145

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Bonding Before Birth: A mobile program to support first-time expectant couples

    A mobile app trial in Singapore tests short weekly exercises for first-time expectant couples to see if it helps reduce depression and improve emotional regulation during pregnancy.

    Recruiting Institute for Human Development and Potential (IHDP), Singapore · Singapore · NCT07483515

  • Single-session intervention to change ambiguity aversion

    This trial tests whether one brief intervention can change how adults with intolerance of uncertainty and anxiety make ambiguous decisions and how their brains respond.

    Recruiting Northwestern University · Chicago, Illinois · NCT06962527

  • Online treatment for emotional disorders in adults with long COVID-19

    This study is testing if an online treatment for emotional issues can help adults with long COVID-19 feel better compared to regular care.

    Recruiting Instituto de Investigación Sanitaria Aragón · Zaragoza, Zaragoza and 1 other locations · NCT06928480

  • Mobile mental health app for young adults

    This study is testing a mobile mental health app called JoyPop to see if it can help young adults aged 18-25 who are waiting for mental health services in Northwestern Ontario manage their emotions better and get the support they need.

    Recruiting Lakehead University · Thunder Bay, Ontario · NCT06239545

  • Mobile mental health app for youth

    This study tests whether the JoyPop mobile app can help young people aged 12-17 manage their emotions better while they wait for mental health services.

    Recruiting Lakehead University · Thunder Bay, Ontario · NCT06239519

  • Mental health app for Indigenous youth

    This study tests whether the JoyPop mental health app can help Indigenous youth in Northwestern Ontario who are waiting for mental health services manage their emotions better.

    Recruiting Lakehead University · Thunder Bay, Ontario · NCT05991154

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.