How sepsis affects the risk of dying in the hospital

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will enroll adults admitted to a cardiology service, including patients with sepsis, nosocomial infection, myocarditis/endocarditis/pericarditis, and cardiology patients without infection as controls. Blood plasma conductivity and dielectric constant will be measured using microwave probes previously validated for non-invasive glucose monitoring, and signals will be captured with an Anritsu VectorStar vector network analyzer. The measured biophysical parameters will be compared between infected and non-infected patients to identify patterns associated with severe infection. The aim is to identify novel, reliable parameters that could supplement existing clinical scores such as SIRS and SOFA for earlier detection of severe infections.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Cardiology patients without documented infection (Control Group)
* Patients with sepsis
* Patients with nosocomial infection
* Patients with myocarditis, endocarditis, or pericarditis
* Ability to provide written informed consent

Exclusion Criteria:

* Patients with severe or chronic medical conditions that may interfere with study results, such as autoimmune diseases, renal or hepatic failure
* Patients taking medications that could affect the measured biophysical parameters, such as corticosteroids or immunosuppressants
* Patients with cancer
* Patients with diseases involving the immune system (e.g., lymphomas, leukemias)
* Patients with congenital or acquired immunodeficiencies (e.g., HIV)
* Patients who are unable to read and sign the informed consent form

Where it's running

• ''Annunziata'' Hospital
  Cosenza, Italy Recruiting

Study contacts

• Study coordinator: Antonio Curcio, Medicine
• Email: antonio.curcio.cardio@unical.it
• Phone: +390984681877

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.