How preoperative anxiety affects vasovagal events during spinal anesthesia

The Effect of Preoperative Anxiety Level on Vasovagal Events During Spinal Anesthesia and the Incidence of Vasovagal Events

Observational Sanliurfa Mehmet Akif Inan Education and Research Hospital · NCT07450014

This project will see if higher anxiety before surgery increases the chance of vasovagal events in adults (18–65, ASA I–II) receiving spinal anesthesia.

Quick facts

Study typeObservational
Enrollment1500 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorSanliurfa Mehmet Akif Inan Education and Research Hospital Academic / other
Locations1 site (Sanliurfa)
Trial IDNCT07450014 on ClinicalTrials.gov

What this trial studies

This is a prospective observational study that measures patients' anxiety before surgery using the Amsterdam Preoperative Anxiety and Information Scale (APAIS) and then monitors for vasovagal events (bradycardia, hypotension, or syncope) during spinal anesthesia. Adult patients aged 18–65 with ASA physical status I–II who are scheduled for procedures under spinal anesthesia will be enrolled. Researchers will record baseline anxiety scores, intraoperative hemodynamic data, and any vasovagal episodes without altering standard anesthesia care. The study is conducted at a single center, Şanlıurfa Mehmet Akif İnan Training and Research Hospital.

Who should consider this trial

Good fit: Adults aged 18–65, ASA I–II, who are planned for surgery under spinal anesthesia and can give informed consent are the ideal candidates.

Not a fit: Patients who are ASA III–V, pregnant or breastfeeding, those for whom spinal anesthesia is contraindicated, or those not receiving spinal anesthesia are unlikely to benefit from the findings.

Why it matters

Potential benefit: If a link is found, clinicians could identify anxious patients beforehand and take steps to reduce vasovagal risk during spinal anesthesia.

How similar studies have performed: Previous observational reports and smaller studies have suggested a connection between preoperative anxiety and vasovagal or hemodynamic events during neuraxial anesthesia, but prospective data remain limited.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* American Soicety of Anesthesiologists (ASA) I-II Patients
* 18-65 years patients

Exclusion Criteria:

* Patients who did not wish to participate in the study voluntarily
* patients for whom spinal anesthesia is contraindicated
* Pregnant and breastfeeding women
* ASA III-IV-V patients

Where this trial is running

Sanliurfa

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Spinal AnesthesiaAnxietyAmsterdam Preoperative Anxiety and Information Scalesencop
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.