How often midline IV catheters are replaced and why
Official title: Study of the Prevalence of Midline Replacements and the Reasons for These Replacements
Run by Centre Hospitalier de Valenciennes · NCT07394296 · Data updated 2026-11-12
See how often midline IV catheters are replaced and the reasons for those replacements in adults who receive a midline.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 984 (estimated) |
| Sponsor | Centre Hospitalier de Valenciennes Research network |
| Locations | 1 site (Valenciennes) |
| Status | Recruiting |
| Started | December 2, 2025 |
| Main results expected | January 5, 2027 |
| Study ends | January 5, 2027 |
| Registry record updated | February 10, 2026 |
| Trial ID | NCT07394296 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults (18+) who consent and receive a first midline catheter of at least 14 cm at the participating hospital for an expected treatment of 28 days or less.
✕Probably not a fit
Patients who need long-term central venous access (like PICC or CVC), children, those with failed midline insertion, under guardianship, or without social security coverage are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study at Centre Hospitalier de Valenciennes will record the frequency of midline catheter replacements and the reasons for replacement in adult patients. Adults over 18 who consent and receive a first midline of at least 14 cm for an expected treatment duration of up to 28 days are eligible, while patients without social security coverage, with failed insertion, or under guardianship are excluded. Study staff will collect information on catheter dwell time, reasons for removal or replacement (for example infection, occlusion, thrombosis, or mechanical issues), and any complications noted during routine care. No experimental treatments are given; clinicians will insert and manage midlines according to local practice and the study will analyze real-world patterns and outcomes.
Why it matters
Potential benefit: If successful, the findings could help clinicians choose and manage midlines better to reduce unnecessary replacements and preserve patients' venous access.
How similar studies have gone: Previous studies have reported mixed complication rates and variable durations of midline use, so this observational work aims to clarify real-world replacement patterns rather than test a new device.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 18 years of age. * Patients who have given their consent to participate in the study. * Patients treated in a hospital unit authorized to insert midlines, or who have a midline inserted by a professional trained in this procedure, in accordance with the local organization of each center. * First insertion for the treatment of a given event with an expected treatment duration of 28 days or less. * Patients treated with a midline catheter at least 14 cm in length. Exclusion Criteria: * No coverage by the social security system * Failure to insert the midline * Patient under guardianship or conservatorship
Where it's running
-
Centre Hospitalier de Valenciennes
Valenciennes, France Recruiting
Study contacts
- Study coordinator: Fanny DEFRANCQ, MD
- Email: defrancq-f@ch-valenciennes.fr
- Phone: 0327149153
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.