How modified-risk claims change the sensory experience of smokeless tobacco
Official title: Influence of Authorized Smokeless Tobacco Product Modified Risk Claims II: Laboratory Assessment of Sensory and Subjective Effects
Run by Roswell Park Cancer Institute · NCT07107139 · Data updated 2026-11-12
This test sees whether modified-risk messages on smokeless tobacco products change sensory experiences and future use intentions for adult daily cigarette smokers.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Roswell Park Cancer Institute Academic / other |
| Locations | 1 site (Buffalo, New York) |
| Status | Recruiting |
| Started | May 11, 2026 |
| Main results expected | May 1, 2027 |
| Study ends | May 1, 2027 |
| Registry record updated | May 22, 2026 |
| Trial ID | NCT07107139 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 21 or older who smoke cigarettes daily (at least 5 per day for one year), live in the specified Western New York counties, are willing to try an oral non-combusted tobacco product, and completed the required preliminary auction are ideal candidates.
✕Probably not a fit
People under 21, non-smokers, pregnant individuals, those unwilling to try oral tobacco, or those living outside the specified counties are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The study enrolls adult daily cigarette smokers who are open to trying a non-combusted oral tobacco product and exposes them in the laboratory to modified-risk messages tied to either Copenhagen or Snus products. Participants provide breath carbon monoxide verification of short-term abstinence and, if applicable, a urine pregnancy test before sessions. Researchers then record sensory and other subjective responses along with participants' intentions to use the products in the future. Results will compare responses across product/message conditions to see if and how claims alter perception or willingness to try these products.
Why it matters
Potential benefit: If successful, results could help regulators and health communicators craft clearer product messages that influence smokers' choices and potentially reduce harm.
How similar studies have gone: Prior lab and survey work shows modified-risk claims can change perceptions and intentions in some cases, but effects are mixed and depend on message wording and product type.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 21 years of age * Residing in 8 counties of Western NY (Erie, Niagara, Cattaraugus, Chautauqua, Allegheny, Livingston, Genesee, Orleans, Wyoming) * Smoke cigarettes every day, at least 5 cigarettes per day, for at least 1 year * Open to trying a non-combusted oral tobacco product * Have the ability to read, write, and communicate in English * Have successfully completed our preliminary Auction study I-4008824 with a bid for Copenhagen and/or General Snus \> $0 * Willing to abstain smoking 8-10 hours prior to each laboratory session and complete breath CO test for verification (\<8ppm) * Female participants must be amenable to taking a pregnancy test (urine) prior to beginning study procedures. * Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure. Exclusion Criteria: * Age ≥ 21 years of age * Residing in 8 counties of Western NY (Erie, Niagara, Cattaraugus, Chautauqua, Allegheny, Livingston, Genesee, Orleans, Wyoming) * Smoke cigarettes every day, at least 5 cigarettes per day, for at least 1 year * Open to trying a non-combusted oral tobacco product * Have the ability to read, write, and communicate in English * Have successfully completed our preliminary Auction study I-4008824 with a bid for Copenhagen and/or General Snus \> $0 * Willing to abstain smoking 8-10 hours prior to each laboratory session and complete breath CO test for verification (\<8ppm) . * Female participants must be amenable to taking a pregnancy test (urine) prior to beginning study procedures. * Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure.
Where it's running
-
Roswell Park
Buffalo, New York, United States Recruiting
Study contacts
- Study coordinator: Ask Rpci
- Email: askrpci@roswellpark.org
- Phone: 1-877-275-7724
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.