How illness severity and death risk relate to breathing and limb muscle strength in ICU patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study enrolling adult ICU patients monitored for at least 48 hours to measure illness severity scores and muscle function without changing clinical care. Investigators will record established severity measures (for example APACHE II) alongside tests of respiratory and peripheral muscle strength and physical function where patients can cooperate. Patients with neuromuscular disease, inability to consent or cooperate, or skin lesions at measurement sites are excluded. The single-site study is conducted at Istinye University Bahçeşehir Liv University Hospital in Istanbul and follows patients during their ICU stay to describe relationships between severity, mortality risk, and muscle function.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Not dependent on mechanical ventilation,

Patient or legal representative provides consent to participate,

Aged 18 years or older,

Monitored in the ICU for at least 48 hours.

Exclusion Criteria:

Unable to obtain ethical consent,

Presence of neuromuscular disease affecting muscle tone,

Patients unable to cooperate during measurement due to impaired consciousness, communication disorder, or other medical reasons,

Presence of infection, open wound, or any lesion impairing skin integrity at the anatomical measurement site.

Where it's running

• Istinye University Bahçeşehir Liv University Hospital
  Istanbul, Esenyurt, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Beyza Tanrıöğen, MSc
• Email: beyza.tanriogen@istinye.edu.tr
• Phone: 00905392359936

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Effects of a caregiver's physical contact on ICU patients

  This study tests whether brief physical contact from a patient’s primary caregiver can influence vital signs in adults in intensive care.

  Recruiting Universidad Autonoma del Estado de Mexico · Mexico City, Mexico City · NCT07761364

• Immunosuppression and ICU-acquired MDROs in critically ill adults

  This study tests how often ICU patients who are immunocompromised acquire or carry resistant bacteria, and how this relates to infections and outcomes.

  Recruiting University Hospital, Lille · Lille · NCT06652126

• Evaluating agitation in critically ill patients using remote video monitoring

  This study is testing a new way to use remote video monitoring to see if it can help doctors better manage agitation in critically ill patients in the ICU.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang and 1 other locations · NCT06543602

• Measuring heart function using AI-guided techniques by minimally trained operators

  This study is testing if a new AI tool can help less experienced staff accurately measure heart function in critically ill ICU patients, so they can better manage their fluid needs.

  Recruiting at 2 sites Assistance Publique - Hôpitaux de Paris · Limoges and 2 other locations · NCT06486467

• Monitoring glucose levels in critically ill patients

  This study looks at how often critically ill patients in the ICU experience low blood sugar and how using continuous glucose monitors can help improve their care.

  Recruiting Universidad Europea de Madrid · Madrid · NCT06234787

• Hepatic Vein Filling Fraction vs TAPSE to Check Right Heart Function in Mechanically Ventilated ICU Patients

  We’re testing if the hepatic vein systolic filling fraction can reliably show how well the right side of the heart is pumping in adults on breathing machines in the ICU.

  Recruiting Menoufia University · Alexandria, Shebin El-Kom · NCT07732114

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.