How hormone and digestion functions and outcomes change after pancreas surgery
Official title: The Analysis of Endocrine-exocrine Functions and Prognosis After Pancreatectomy
Run by National Taiwan University Hospital · NCT07396662 · Data updated 2026-11-12
This project will look back at medical records to see if different pancreatectomy methods, margin clearance, and how much pancreas is left affect hormone (endocrine) and digestion (exocrine) function and overall outcomes in adults who had pancreas surgery at our hospital.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 75 Years |
| Sex | All |
| Enrollment | 3500 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei, Taiwan) |
| Status | Recruiting |
| Started | January 1, 2016 |
| Main results expected | December 31, 2034 |
| Study ends | December 31, 2034 |
| Registry record updated | February 9, 2026 |
| Trial ID | NCT07396662 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 20 to 75 who underwent pancreatectomy at National Taiwan University Hospital with available preoperative and postoperative clinical, laboratory, and imaging data are ideal candidates for inclusion.
✕Probably not a fit
Patients younger than 20, older than 75, pregnant individuals, or those without adequate pre/postoperative records are unlikely to be included or benefit from the study findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a retrospective observational project using records from patients who underwent pancreatectomy at National Taiwan University Hospital. Investigators will collect baseline data, preoperative and postoperative blood tests (including blood counts, biochemistry, tumor markers, glucose- and lipid-related tests), and pre/postoperative imaging (CT, MRI, ultrasound, PET, endoscopy). They will compare surgical approach, margin clearance rates, and remnant pancreatic volume against changes in endocrine and exocrine function, quality of life, and disease prognosis. Analysis aims to identify surgery-related factors linked to functional outcomes and long-term prognosis.
Why it matters
Potential benefit: If successful, the findings could help surgeons and clinicians choose approaches and follow-up care that better preserve pancreatic function and improve quality of life and prognosis after pancreatectomy.
How similar studies have gone: Prior research has shown that pancreatic resection commonly affects endocrine and exocrine function and that remnant pancreatic volume relates to diabetes risk, so this retrospective comparison builds on established findings rather than being entirely novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients scheduled for pancreatectomy Exclusion Criteria: * Age under 20 years or older than 75 years; Pregnancy
Where it's running
-
National Taiwan University Hospital
Taipei, Taiwan, Taiwan Recruiting
Study contacts
- Study coordinator: Yu Wen Tien, Ph.D.
- Email: ywtien5106@ntu.edu.tw
- Phone: 0972651427
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.