How health and motivation change during the 13-week KHEOPS physical activity program for women treated for breast cancer

Evolution of Psychological Determinants of Physical Activity and Cancer-related Psychological Symptoms in Patients Undergoing Treatment for Breast Cancer and Following a Physical Activity Program

Observational Centre Leon Berard · NCT07515326

This study will see how clinical symptoms and motivation change during a 13-week KHEOPS physical activity program for women with non-metastatic breast cancer.

Quick facts

Study typeObservational
Enrollment80 (estimated)
Ages18 Years and up
SexFemale
SponsorCentre Leon Berard Academic / other
Locations1 site (Lyon)
Trial IDNCT07515326 on ClinicalTrials.gov

What this trial studies

This is a single-center, prospective observational study following women enrolled in the 13-week KHEOPS adapted physical activity (APA) program at Centre Léon Bérard. Participants complete two short online questionnaires each week and attend KHEOPS sessions either in person or remotely while clinical and motivational constructs derived from M‑PAC are recorded over time. Secondary aims include measuring the feasibility of the psychological measures and program participation, tracking cancer-related psychological symptoms, and relating changes in psychological factors to adherence and post-program physical activity levels. The study focuses on women undergoing or after surgery for non-metastatic breast cancer who can use a smartphone, tablet, or computer and read French.

Who should consider this trial

Good fit: Women aged 18 or older with non-metastatic breast cancer who are enrolled in the KHEOPS program at Centre Léon Bérard, can use a smartphone/computer/tablet, and read French are ideal candidates.

Not a fit: Patients with metastatic disease, those unable to complete online questionnaires or be followed for the study duration, or those without access to the required devices are unlikely to benefit from the study findings.

Why it matters

Potential benefit: If successful, the findings could help tailor support to boost motivation and adherence to physical activity during and after treatment, potentially improving quality of life.

How similar studies have performed: Previous supervised and remote physical activity programs and M‑PAC–based measures have shown feasibility and improvements in quality of life and adherence in breast cancer populations, though applying them specifically within the KHEOPS program is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria

* Woman aged ≥ 18 years
* Diagnosed with non-metastatic breast cancer
* Undergoing treatment or after surgery
* Participating in the CLB KHEOPS program, either face-to-face or distance learning
* Have a smartphone, computer or tablet to answer the 2 weekly online weekly online questionnaires and to follow APA sessions for patients following the patients following the KHEOPS program remotely
* Having received a study information note and having made a declaration of non-opposition
* Affiliated with a social security scheme
* Able to read, write and understand French

Exclusion Criteria:

* Unable to be followed for medical, social, family, geographical or psychological reasons, for the duration of the study.
* Have difficulty completing a questionnaire alone
* Deprived of liberty by judicial or administrative decision, or adults protected by law
* Concurrently participating in another PA study

Where this trial is running

Lyon

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast CancerBreast cancerphysical activtyKHEOPS program
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.