How feeling out of control affects detail-focused thinking in people with anorexia
Official title: Influence of Control Deprivation on the Use of the Analytical Cognitive Style in Anorexic Subjects
Run by Centre Hospitalier Henri Laborit · NCT07274722 · Data updated 2026-11-12
This test will try to see if temporarily lowering someone’s sense of control makes people with anorexia focus more on details of their body and thinking style.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 54 (estimated) |
| Sponsor | Centre Hospitalier Henri Laborit Academic / other |
| Locations | 1 site (Poitiers) |
| Status | Recruiting |
| Started | April 4, 2024 |
| Main results expected | April 3, 2028 |
| Study ends | April 3, 2028 |
| Registry record updated | October 22, 2026 |
| Trial ID | NCT07274722 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults receiving treatment for anorexia nervosa (or clinically significant subthreshold anorexia) at Centre Hospitalier Henri Laborit or CHU de Poitiers are the intended participants.
✕Probably not a fit
People who are not treated at the participating Poitiers centers, who have other primary eating disorders, unstable medical status, or cannot complete in-person tasks are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
People with anorexia often use a detail-focused, analytical way of thinking that may contribute to fragmented body perception, and a strong need for control is commonly reported in the disorder. This interventional protocol exposes participants to a cognitive control deprivation task designed to temporarily reduce their feeling of control and then measures changes in analytical processing and body-related perception. Eligible participants are patients treated at the participating Poitiers centers who meet DSM-5 criteria for anorexia nervosa or have subclinical symptoms requiring care. Outcomes combine behavioral tasks and self-report measures to detect shifts in cognitive style and body image following the manipulation.
Why it matters
Potential benefit: If successful, results could help target treatments by showing whether addressing control needs reduces detail-focused thinking and improves body perception in anorexia.
How similar studies have gone: Some non-clinical research shows loss of control can prompt more analytical thinking, but a causal link in anorexia nervosa has not been demonstrated and this approach is relatively novel in this population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Be undergoing treatment at Centre Hospitalier Laborit (CHL) or Centre Hospitalier Universitaire (CHU) de Poitiers for an Eating Disorder (ED) of the Anorexia Nervosa type. * Patients must meet the diagnostic criteria for Anorexia Nervosa according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5; American Psychiatric Association, APA, 2013), or present a sub-clinical symptomatology requiring treatment: (A) Restriction of energy intake relative to requirements, leading to a significantly low body weight, taking into account age, sex, developmental stage, and physical health; (B) Intense fear of gaining weight or becoming fat, or persistent behavior that interferes with weight gain, even when at a significantly low weight; (C) Disturbance in the way body weight or shape is experienced, undue influence of body weight or shape on self-esteem, or persistent lack of recognition of the seriousness of the current low body weight. Exclusion Criteria: * Objection of the referring therapist * Currently receiving cognitive remediation targeting mental flexibility and central coherence * Body Mass Index (BMI) less than 14 * Inability to understand instructions in French * Visual impairment or dyslexia
Where it's running
-
Centre Hospitalier Henri Laborit
Poitiers, France Recruiting
Study contacts
- Study coordinator: Nematollah Jaafari, Professor
- Email: nemat.jaafari@ch-poitiers.fr
- Phone: +33 5 16 52 61 18
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Specialist Supportive Clinical Management for teens with anorexia or atypical anorexia
This study tests a teen-focused SSCM approach to help 13-17 year-olds with anorexia nervosa or atypical anorexia nervosa when other treatments haven’t worked or can’t be used.
-
Identifying Signatures of Gut Interoception in Functional Dyspepsia and Anorexia Nervosa
This study tests how the gut-brain connection works in people with functional dyspepsia or anorexia nervosa using brain imaging.
-
Online FBT-DBT for Caregivers of Teens with Anorexia Nervosa
This online program tests a combination of family-based and DBT skills to help caregivers of teens with anorexia nervosa manage stress and improve family support.
-
Eating Disorder Dynamic Intervention
A digital program is tested to help adults with eating disorders by sending real-time, personalized coping tips based on smartphone surveys and sensor data.
-
Hormone and metabolic patterns in hypothalamus-like brain cells from people with anorexia nervosa
This study will test whether hypothalamic-like neurons made from adult women with long-standing anorexia nervosa respond differently to metabolic hormones than neurons from healthy women.
-
Narrative medicine workshops to support teens and young adults with anorexia nervosa (virtual)
This program tests whether a six-week series of narrative medicine workshops can help 16–25-year-olds with anorexia nervosa express themselves, reflect, and build resilience.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.